Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 240991..241592 Replicon chromosome
Accession NZ_CP087178
Organism Pseudomonas sp. B21-036

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LOY33_RS01105 Protein ID WP_258660755.1
Coordinates 241278..241592 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LOY33_RS01100 Protein ID WP_054915914.1
Coordinates 240991..241278 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY33_RS01075 (LOY33_01075) 236405..236887 - 483 WP_054915912.1 ATP-dependent zinc protease -
LOY33_RS01080 (LOY33_01080) 236997..237398 + 402 WP_043861624.1 S4 domain-containing protein -
LOY33_RS01085 (LOY33_01085) 237395..238198 - 804 WP_058541684.1 phosphatase PAP2 family protein -
LOY33_RS01090 (LOY33_01090) 238304..239206 + 903 WP_043861626.1 Hsp33 family molecular chaperone HslO -
LOY33_RS01095 (LOY33_01095) 239386..240927 + 1542 WP_043861627.1 phosphoenolpyruvate carboxykinase -
LOY33_RS01100 (LOY33_01100) 240991..241278 - 288 WP_054915914.1 helix-turn-helix domain-containing protein Antitoxin
LOY33_RS01105 (LOY33_01105) 241278..241592 - 315 WP_258660755.1 hypothetical protein Toxin
LOY33_RS01110 (LOY33_01110) 241772..242200 + 429 WP_258660756.1 thioesterase family protein -
LOY33_RS01115 (LOY33_01115) 242213..242869 - 657 WP_043861630.1 response regulator transcription factor -
LOY33_RS01120 (LOY33_01120) 242909..243976 - 1068 WP_258660758.1 chemotaxis response regulator protein-glutamate methylesterase -
LOY33_RS01125 (LOY33_01125) 243973..244785 - 813 WP_258660761.1 protein-glutamate O-methyltransferase CheR -
LOY33_RS01130 (LOY33_01130) 244786..245298 - 513 WP_043861633.1 chemotaxis protein CheW -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(36-88)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11781.54 Da        Isoelectric Point: 9.8352

>T225019 WP_258660755.1 NZ_CP087178:c241592-241278 [Pseudomonas sp. B21-036]
MLFIETSVFTSDVSSHLDDHEYLSLQVYLAEHPEAGDLIEDTGGLRKIRWAAKSKGKSGGVRVIYYYAVSASQIRLLLIY
RKGIHDTLTKKQKAVLRSLNQGWK

Download         Length: 315 bp

>T225019 NZ_CP120837:3602188-3602445 [Salmonella enterica subsp. enterica]
ATGAATGCCTCCGGCGTCAGCGTCCGCCACATCAACAGCAAAACCCACATGACCACCTATTACTCACAAATCCCCAGCCT
GCATCTTAAGGGCGACTGGCTGGAAGAAGCGGGATTTAAGACCGGGCGCGGCGTCACCGTGAAGATTTCACAGGGGTGTA
TTGTGCTGATGGCGGACAGTAACGAGGAGCAGAAGCTGCGCGAGCAGCTTTATCAGGCTAAACAGGTGGTTAAGGGAATT
AAGGACGTGCTGGTTTAG

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10768.29 Da        Isoelectric Point: 7.1696

>AT225019 WP_054915914.1 NZ_CP087178:c241278-240991 [Pseudomonas sp. B21-036]
MDRNLFGRLVDSMTEMAEIDRGERKPSREFKVDAMQVRAIREATGLTQERFAQCIDVPLGTLRNWEQGRRAPEGPARALL
RAIHNDPEHVLAALA

Download         Length: 288 bp

>AT225019 NZ_CP120837:c3602363-3602031 [Salmonella enterica subsp. enterica]
TCCGCCATCAGCACAATACACCCCTGTGAAATCTTCACGGTGACGCCGCGCCCGGTCTTAAATCCCGCTTCTTCCAGCCA
GTCGCCCTTAAGATGCAGGCTGGGGATTTGTGAGTAATAGGTGGTCATGTGGGTTTTGCTGTTGATGTGGCGGACGCTGA
CGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTATCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTG
AGCGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCC
GGGGCCGTATTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References