Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/- |
Location | 4393876..4394581 | Replicon | chromosome |
Accession | NZ_CP087176 | ||
Organism | Pseudomonas sp. B21-040 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | LOY55_RS20115 | Protein ID | WP_223522550.1 |
Coordinates | 4393876..4394277 (+) | Length | 134 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | LOY55_RS20120 | Protein ID | WP_046032497.1 |
Coordinates | 4394267..4394581 (+) | Length | 105 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LOY55_RS20105 (LOY55_20070) | 4390504..4392036 | + | 1533 | WP_046032494.1 | NADH-quinone oxidoreductase subunit M | - |
LOY55_RS20110 (LOY55_20075) | 4392044..4393507 | + | 1464 | WP_046032495.1 | NADH-quinone oxidoreductase subunit NuoN | - |
LOY55_RS20115 (LOY55_20080) | 4393876..4394277 | + | 402 | WP_223522550.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
LOY55_RS20120 (LOY55_20085) | 4394267..4394581 | + | 315 | WP_046032497.1 | transcriptional regulator | Antitoxin |
LOY55_RS20125 (LOY55_20090) | 4394758..4395738 | + | 981 | WP_256594780.1 | OprD family outer membrane porin | - |
LOY55_RS20130 (LOY55_20095) | 4396077..4397819 | - | 1743 | WP_223522549.1 | ABC transporter substrate-binding protein | - |
LOY55_RS20135 (LOY55_20100) | 4397867..4398139 | - | 273 | WP_046032507.1 | DUF2160 domain-containing protein | - |
LOY55_RS20140 (LOY55_20105) | 4398150..4398950 | - | 801 | WP_046032508.1 | carbohydrate ABC transporter permease | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 134 a.a. Molecular weight: 15864.93 Da Isoelectric Point: 9.2190
>T225008 WP_223522550.1 NZ_CP087176:4393876-4394277 [Pseudomonas sp. B21-040]
MTYSVIETTLYAGNVQNRDALFIELPAFQKHRDDYLDDDLFRSFQLELLKNPAAGDLIEGTGGLRKIRFFDQRRGKGKRS
GLRVIYYWWSGFEQFWLFTVYSKNEHDDLSPAQKKLFRQMLNREINTRTHYET
MTYSVIETTLYAGNVQNRDALFIELPAFQKHRDDYLDDDLFRSFQLELLKNPAAGDLIEGTGGLRKIRFFDQRRGKGKRS
GLRVIYYWWSGFEQFWLFTVYSKNEHDDLSPAQKKLFRQMLNREINTRTHYET
Download Length: 402 bp
>T225008 NZ_CP120736:1244722-1245105 [Lacticaseibacillus rhamnosus]
ATGGATGTAACAGTCAAACGCGGGGATGTATTTTTCGCCGATTTATCGCCGGTTGTCGGGTCGGAACAAGGCGGCAACCG
GCCCGTACTTATTATTCAAAACAATGTTGGTAACCATTATAGCCCCACTGTTATCGTGGCTGCCATTACCTCCAAAATCC
AAAAACCCAAAATGCCCACCCATGTCGGTTTGCGCGCCAAGCAAGACGGGGTTGAGCGTAATTCAGTCATTTTGCTTGAA
CAGATTCGTACAATTGATAAGCAACGGTTACAGGCACGCGTTACCGCTCTTTCAAGTGCCAAAATGGCAGCGGTGGATCG
GGCACTGGCGATATCGGTCGGACTCGTCAGCTTGCCTAAGCCGAAAACATATAATAAAAACTAA
ATGGATGTAACAGTCAAACGCGGGGATGTATTTTTCGCCGATTTATCGCCGGTTGTCGGGTCGGAACAAGGCGGCAACCG
GCCCGTACTTATTATTCAAAACAATGTTGGTAACCATTATAGCCCCACTGTTATCGTGGCTGCCATTACCTCCAAAATCC
AAAAACCCAAAATGCCCACCCATGTCGGTTTGCGCGCCAAGCAAGACGGGGTTGAGCGTAATTCAGTCATTTTGCTTGAA
CAGATTCGTACAATTGATAAGCAACGGTTACAGGCACGCGTTACCGCTCTTTCAAGTGCCAAAATGGCAGCGGTGGATCG
GGCACTGGCGATATCGGTCGGACTCGTCAGCTTGCCTAAGCCGAAAACATATAATAAAAACTAA
Antitoxin
Download Length: 105 a.a. Molecular weight: 11904.78 Da Isoelectric Point: 9.9896
>AT225008 WP_046032497.1 NZ_CP087176:4394267-4394581 [Pseudomonas sp. B21-040]
MKRDIFSELIEGLDALADERQGKITLRSHKVQLPKLMPITAEEVVAIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATPN
AQATTLIRLVERFPQTIEQLAALT
MKRDIFSELIEGLDALADERQGKITLRSHKVQLPKLMPITAEEVVAIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATPN
AQATTLIRLVERFPQTIEQLAALT
Download Length: 315 bp
>AT225008 NZ_CP120736:1244454-1244702 [Lacticaseibacillus rhamnosus]
ATGAAGAAGGAAACGTCAGTAACGGTCGCGCTTGATAGTGCTATCAAAGCGCGTTTGGATGCCTATTGCGAGTTGAATGA
TATGGGTGTTCAGGATGTCATTACTGAAGCAGTGGCGAAGTTTTTGCAGTCACAAGCACCTGAGATCAATCAATTGATTT
CTGGCTATGTGGCAATGGGACAAATCAATACGGAAATCAGCCATGCTTTCTCCGCCTGCGAAAGTGAGGCATACGCCCAT
ATTCGATAA
ATGAAGAAGGAAACGTCAGTAACGGTCGCGCTTGATAGTGCTATCAAAGCGCGTTTGGATGCCTATTGCGAGTTGAATGA
TATGGGTGTTCAGGATGTCATTACTGAAGCAGTGGCGAAGTTTTTGCAGTCACAAGCACCTGAGATCAATCAATTGATTT
CTGGCTATGTGGCAATGGGACAAATCAATACGGAAATCAGCCATGCTTTCTCCGCCTGCGAAAGTGAGGCATACGCCCAT
ATTCGATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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