225008

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4393876..4394581 Replicon chromosome
Accession NZ_CP087176
Organism Pseudomonas sp. B21-040

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LOY55_RS20115 Protein ID WP_223522550.1
Coordinates 4393876..4394277 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LOY55_RS20120 Protein ID WP_046032497.1
Coordinates 4394267..4394581 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY55_RS20105 (LOY55_20070) 4390504..4392036 + 1533 WP_046032494.1 NADH-quinone oxidoreductase subunit M -
LOY55_RS20110 (LOY55_20075) 4392044..4393507 + 1464 WP_046032495.1 NADH-quinone oxidoreductase subunit NuoN -
LOY55_RS20115 (LOY55_20080) 4393876..4394277 + 402 WP_223522550.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY55_RS20120 (LOY55_20085) 4394267..4394581 + 315 WP_046032497.1 transcriptional regulator Antitoxin
LOY55_RS20125 (LOY55_20090) 4394758..4395738 + 981 WP_256594780.1 OprD family outer membrane porin -
LOY55_RS20130 (LOY55_20095) 4396077..4397819 - 1743 WP_223522549.1 ABC transporter substrate-binding protein -
LOY55_RS20135 (LOY55_20100) 4397867..4398139 - 273 WP_046032507.1 DUF2160 domain-containing protein -
LOY55_RS20140 (LOY55_20105) 4398150..4398950 - 801 WP_046032508.1 carbohydrate ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 15864.93 Da        Isoelectric Point: 9.2190

>T225008 WP_223522550.1 NZ_CP087176:4393876-4394277 [Pseudomonas sp. B21-040]
MTYSVIETTLYAGNVQNRDALFIELPAFQKHRDDYLDDDLFRSFQLELLKNPAAGDLIEGTGGLRKIRFFDQRRGKGKRS
GLRVIYYWWSGFEQFWLFTVYSKNEHDDLSPAQKKLFRQMLNREINTRTHYET

Download         Length: 402 bp

>T225008 NZ_CP120736:1244722-1245105 [Lacticaseibacillus rhamnosus]
ATGGATGTAACAGTCAAACGCGGGGATGTATTTTTCGCCGATTTATCGCCGGTTGTCGGGTCGGAACAAGGCGGCAACCG
GCCCGTACTTATTATTCAAAACAATGTTGGTAACCATTATAGCCCCACTGTTATCGTGGCTGCCATTACCTCCAAAATCC
AAAAACCCAAAATGCCCACCCATGTCGGTTTGCGCGCCAAGCAAGACGGGGTTGAGCGTAATTCAGTCATTTTGCTTGAA
CAGATTCGTACAATTGATAAGCAACGGTTACAGGCACGCGTTACCGCTCTTTCAAGTGCCAAAATGGCAGCGGTGGATCG
GGCACTGGCGATATCGGTCGGACTCGTCAGCTTGCCTAAGCCGAAAACATATAATAAAAACTAA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11904.78 Da        Isoelectric Point: 9.9896

>AT225008 WP_046032497.1 NZ_CP087176:4394267-4394581 [Pseudomonas sp. B21-040]
MKRDIFSELIEGLDALADERQGKITLRSHKVQLPKLMPITAEEVVAIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATPN
AQATTLIRLVERFPQTIEQLAALT

Download         Length: 315 bp

>AT225008 NZ_CP120736:1244454-1244702 [Lacticaseibacillus rhamnosus]
ATGAAGAAGGAAACGTCAGTAACGGTCGCGCTTGATAGTGCTATCAAAGCGCGTTTGGATGCCTATTGCGAGTTGAATGA
TATGGGTGTTCAGGATGTCATTACTGAAGCAGTGGCGAAGTTTTTGCAGTCACAAGCACCTGAGATCAATCAATTGATTT
CTGGCTATGTGGCAATGGGACAAATCAATACGGAAATCAGCCATGCTTTCTCCGCCTGCGAAAGTGAGGCATACGCCCAT
ATTCGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References