Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 3677577..3678231 Replicon chromosome
Accession NZ_CP087168
Organism Pseudomonas sp. B21-048

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LOY56_RS17220 Protein ID WP_258622731.1
Coordinates 3677577..3677927 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A2S8HJ53
Locus tag LOY56_RS17225 Protein ID WP_030130910.1
Coordinates 3677917..3678231 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY56_RS17210 (LOY56_17170) 3674218..3675750 + 1533 WP_258615901.1 NADH-quinone oxidoreductase subunit M -
LOY56_RS17215 (LOY56_17175) 3675758..3677221 + 1464 WP_008014910.1 NADH-quinone oxidoreductase subunit NuoN -
LOY56_RS17220 (LOY56_17180) 3677577..3677927 + 351 WP_258622731.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY56_RS17225 (LOY56_17185) 3677917..3678231 + 315 WP_030130910.1 XRE family transcriptional regulator Antitoxin
LOY56_RS17230 (LOY56_17190) 3678409..3680151 - 1743 WP_258615903.1 ABC transporter substrate-binding protein -
LOY56_RS17235 (LOY56_17195) 3680199..3680471 - 273 WP_258622733.1 DUF2160 domain-containing protein -
LOY56_RS17240 (LOY56_17200) 3680482..3681282 - 801 WP_007896138.1 carbohydrate ABC transporter permease -
LOY56_RS17245 (LOY56_17205) 3681291..3682157 - 867 WP_258615904.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13846.71 Da        Isoelectric Point: 6.4811

>T224975 WP_258622731.1 NZ_CP087168:3677577-3677927 [Pseudomonas sp. B21-048]
MDALFIELPVFQKHRSDYLDDDLFHRFQQELLQTPEAGDVVEGTGGLRKIRVVDERRSKGKRGGLRVIYYWWSGFDQFWL
FTLYGKNEQDDLTPQQKKLLKEMLYREIKARTSDET

Download         Length: 351 bp

>T224975 NZ_CP120671:c4501213-4501110 [Salmonella enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11861.74 Da        Isoelectric Point: 10.5480

>AT224975 WP_030130910.1 NZ_CP087168:3677917-3678231 [Pseudomonas sp. B21-048]
MKRDIFSELVEGFEALADERQGKVTLRTHKVKLAKLAPITAEEVVGIRQQLNLSRPVFAMYLRTNTRTLENWEQGRAKPN
AQATTLIRLVERFPETVQQLAALT

Download         Length: 315 bp

>AT224975 NZ_CP120671:4501108-4501253 [Salmonella enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2S8HJ53

References