Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 3677577..3678231 Replicon chromosome
Accession NZ_CP087168
Organism Pseudomonas sp. B21-048

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LOY56_RS17220 Protein ID WP_258622731.1
Coordinates 3677577..3677927 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A2S8HJ53
Locus tag LOY56_RS17225 Protein ID WP_030130910.1
Coordinates 3677917..3678231 (+) Length 105 a.a.

Genomic Context

LOY56_RS17210LOY56_RS17215LOY56_RS17220LOY56_RS17225LOY56_RS17230LOY56_RS17235LOY56_RS17240LOY56_RS17245
Location: 3674218..3675750 (1533 bp)
Type: Others
Protein ID: WP_258615901.1
Location: 3675758..3677221 (1464 bp)
Type: Others
Protein ID: WP_008014910.1
Location: 3677577..3677927 (351 bp)
Type: Toxin
Protein ID: WP_258622731.1
Location: 3677917..3678231 (315 bp)
Type: Antitoxin
Protein ID: WP_030130910.1
Location: 3678409..3680151 (1743 bp)
Type: Others
Protein ID: WP_258615903.1
Location: 3680199..3680471 (273 bp)
Type: Others
Protein ID: WP_258622733.1
Location: 3680482..3681282 (801 bp)
Type: Others
Protein ID: WP_007896138.1
Location: 3681291..3682157 (867 bp)
Type: Others
Protein ID: WP_258615904.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LOY56_RS17210 (LOY56_17170)3674218..3675750+1533WP_258615901.1NADH-quinone oxidoreductase subunit M-
LOY56_RS17215 (LOY56_17175)3675758..3677221+1464WP_008014910.1NADH-quinone oxidoreductase subunit NuoN-
LOY56_RS17220 (LOY56_17180)3677577..3677927+351WP_258622731.1type II toxin-antitoxin system RelE/ParE family toxinToxin
LOY56_RS17225 (LOY56_17185)3677917..3678231+315WP_030130910.1XRE family transcriptional regulatorAntitoxin
LOY56_RS17230 (LOY56_17190)3678409..3680151-1743WP_258615903.1ABC transporter substrate-binding protein-
LOY56_RS17235 (LOY56_17195)3680199..3680471-273WP_258622733.1DUF2160 domain-containing protein-
LOY56_RS17240 (LOY56_17200)3680482..3681282-801WP_007896138.1carbohydrate ABC transporter permease-
LOY56_RS17245 (LOY56_17205)3681291..3682157-867WP_258615904.1sugar ABC transporter permease-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13846.71 Da        Isoelectric Point: 6.4811

>T224975 WP_258622731.1 NZ_CP087168:3677577-3677927 [Pseudomonas sp. B21-048]
MDALFIELPVFQKHRSDYLDDDLFHRFQQELLQTPEAGDVVEGTGGLRKIRVVDERRSKGKRGGLRVIYYWWSGFDQFWL
FTLYGKNEQDDLTPQQKKLLKEMLYREIKARTSDET

Download         Length: 351 bp

>T224975 NZ_CP120671:c4501213-4501110 [Salmonella enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11861.74 Da        Isoelectric Point: 10.5480

>AT224975 WP_030130910.1 NZ_CP087168:3677917-3678231 [Pseudomonas sp. B21-048]
MKRDIFSELVEGFEALADERQGKVTLRTHKVKLAKLAPITAEEVVGIRQQLNLSRPVFAMYLRTNTRTLENWEQGRAKPN
AQATTLIRLVERFPETVQQLAALT

Download         Length: 315 bp

>AT224975 NZ_CP120671:4501108-4501253 [Salmonella enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A2S8HJ53

References