Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/- |
| Location | 4871691..4872346 | Replicon | chromosome |
| Accession | NZ_CP087166 | ||
| Organism | Pseudomonas sp. B21-051 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | - |
| Locus tag | LOY52_RS21860 | Protein ID | WP_096795494.1 |
| Coordinates | 4872002..4872346 (-) | Length | 115 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | A0A031G2F6 |
| Locus tag | LOY52_RS21855 | Protein ID | WP_047599259.1 |
| Coordinates | 4871691..4872005 (-) | Length | 105 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LOY52_RS21830 (LOY52_21800) | 4867215..4867733 | - | 519 | WP_258675954.1 | peptide-methionine (R)-S-oxide reductase MsrB | - |
| LOY52_RS21835 (LOY52_21805) | 4867885..4868595 | + | 711 | WP_258675955.1 | response regulator transcription factor | - |
| LOY52_RS21840 (LOY52_21810) | 4868592..4870112 | + | 1521 | WP_258675956.1 | HAMP domain-containing sensor histidine kinase | - |
| LOY52_RS21845 (LOY52_21815) | 4870232..4870933 | + | 702 | WP_258675957.1 | hypothetical protein | - |
| LOY52_RS21850 (LOY52_21820) | 4871001..4871492 | - | 492 | WP_258675958.1 | RidA family protein | - |
| LOY52_RS21855 (LOY52_21825) | 4871691..4872005 | - | 315 | WP_047599259.1 | helix-turn-helix domain-containing protein | Antitoxin |
| LOY52_RS21860 (LOY52_21830) | 4872002..4872346 | - | 345 | WP_096795494.1 | toxin | Toxin |
| LOY52_RS21865 (LOY52_21835) | 4872473..4873360 | - | 888 | WP_003227980.1 | heme o synthase | - |
| LOY52_RS21870 (LOY52_21840) | 4873371..4873706 | - | 336 | WP_003227981.1 | cytochrome o ubiquinol oxidase subunit IV | - |
| LOY52_RS21875 (LOY52_21845) | 4873706..4874329 | - | 624 | WP_003227982.1 | cytochrome o ubiquinol oxidase subunit III | - |
| LOY52_RS21880 (LOY52_21850) | 4874333..4876360 | - | 2028 | WP_007968380.1 | cytochrome o ubiquinol oxidase subunit I | - |
| LOY52_RS21885 (LOY52_21855) | 4876364..4877305 | - | 942 | WP_027612162.1 | ubiquinol oxidase subunit II | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 115 a.a. Molecular weight: 13462.36 Da Isoelectric Point: 9.8602
>T224960 WP_096795494.1 NZ_CP087166:c4872346-4872002 [Pseudomonas sp. B21-051]
MRTVFFETTIFTASVGHYLTDDEYRELQNYLQCNPASGDVIPRTGGFRKLRWSDARRGKGRRGGLRVIYYWLMNDRQFWM
FAIYDKDELENLSAEKEKALKKAIEIELRKRGAS
MRTVFFETTIFTASVGHYLTDDEYRELQNYLQCNPASGDVIPRTGGFRKLRWSDARRGKGRRGGLRVIYYWLMNDRQFWM
FAIYDKDELENLSAEKEKALKKAIEIELRKRGAS
Download Length: 345 bp
>T224960 NZ_CP120641:c1267096-1266350 [Bacillus velezensis]
ATGCTTTTGTTTTTTCAGATCATGGTGTGGACGATGGCGGCCGCACTCATTTTATATGTGTACGCATCCTGGCGGTATGA
GGCAAAGGTAAAAGAAAAAATGTTTGCCATCCGTAAAACGTGGTATTTACTATTTGTACTGGGCTCCATGGTCTATTGGA
CATATGATCCCGAATCGCTCTTTGCCGCATGGAGACAATATTTGATTGTTGCCGTCTGCTTTGCCCTTATTGATGCGTTT
ATCTTTTTGAGCGCGTATATCAAAAAGCTCGCCGGCAATGAATTAGAGACGGATACGCGGGAAATTTTAGAAGAAAATAA
CGAAATGCTTCACTCCTATCTTGAAAAACTGAAAACCTATCAATATCTGTTGAAAAATGAACCGATCCATGTATATTATG
GAAGTACAGAAGCTTATGCGGAAGGCATCAGCAGATTGCTGGCCGCTTATGCCGAAAAAATGAATGTCACGGCTTCCTTG
TGCGACTATTCCGCACAATCGGATAAGGACCGCTTGACGGAGCATATGCCTGATGCGGCGGACGTTCAGTCCCGTCTTAA
CCGTAAAGACGTCTACTATGATCAAAAAGGCAGGCTTGTGCTTATTCCGTTTACAGTCCAGAACCGCCATTACGTGATCA
AACTCACGTCGGAAAACCTGTTGACGGAATTCGATTATTTGCTTTTCACATCGCTAACGAGCATTTATGATTTAATGCTG
CCAATAGAAGAGGAAGGTGACGGTTAA
ATGCTTTTGTTTTTTCAGATCATGGTGTGGACGATGGCGGCCGCACTCATTTTATATGTGTACGCATCCTGGCGGTATGA
GGCAAAGGTAAAAGAAAAAATGTTTGCCATCCGTAAAACGTGGTATTTACTATTTGTACTGGGCTCCATGGTCTATTGGA
CATATGATCCCGAATCGCTCTTTGCCGCATGGAGACAATATTTGATTGTTGCCGTCTGCTTTGCCCTTATTGATGCGTTT
ATCTTTTTGAGCGCGTATATCAAAAAGCTCGCCGGCAATGAATTAGAGACGGATACGCGGGAAATTTTAGAAGAAAATAA
CGAAATGCTTCACTCCTATCTTGAAAAACTGAAAACCTATCAATATCTGTTGAAAAATGAACCGATCCATGTATATTATG
GAAGTACAGAAGCTTATGCGGAAGGCATCAGCAGATTGCTGGCCGCTTATGCCGAAAAAATGAATGTCACGGCTTCCTTG
TGCGACTATTCCGCACAATCGGATAAGGACCGCTTGACGGAGCATATGCCTGATGCGGCGGACGTTCAGTCCCGTCTTAA
CCGTAAAGACGTCTACTATGATCAAAAAGGCAGGCTTGTGCTTATTCCGTTTACAGTCCAGAACCGCCATTACGTGATCA
AACTCACGTCGGAAAACCTGTTGACGGAATTCGATTATTTGCTTTTCACATCGCTAACGAGCATTTATGATTTAATGCTG
CCAATAGAAGAGGAAGGTGACGGTTAA
Antitoxin
Download Length: 105 a.a. Molecular weight: 11836.82 Da Isoelectric Point: 10.2426
>AT224960 WP_047599259.1 NZ_CP087166:c4872005-4871691 [Pseudomonas sp. B21-051]
MKKRDLFAELMQGVEEMAAHREGKITLRNTVVEDKPVPEVGAQEIVALREKLHMSQAVFAKRIRTSPSTLRNWEQEKSKP
NAQAALLIRLVEKFPDMVERLGAV
MKKRDLFAELMQGVEEMAAHREGKITLRNTVVEDKPVPEVGAQEIVALREKLHMSQAVFAKRIRTSPSTLRNWEQEKSKP
NAQAALLIRLVEKFPDMVERLGAV
Download Length: 315 bp
>AT224960 NZ_CP120641:c1266349-1266179 [Bacillus velezensis]
ATGGAGCAGGCATTTCAAAACGGGCAGCCGGAACAAAGAGCGAAACCGTTCAAAATGTTTAAAAAACGTTCAATGACAAG
TATCGCAAGTTACCAGGTCAGCCCTCATACCGCCAGAATTTTCAAAGAAAACGAGCGGCTGATTGACAAGTATAAACAAA
AAAAAGCTTGA
ATGGAGCAGGCATTTCAAAACGGGCAGCCGGAACAAAGAGCGAAACCGTTCAAAATGTTTAAAAAACGTTCAATGACAAG
TATCGCAAGTTACCAGGTCAGCCCTCATACCGCCAGAATTTTCAAAGAAAACGAGCGGCTGATTGACAAGTATAAACAAA
AAAAAGCTTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|