224956

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 304152..304756 Replicon chromosome
Accession NZ_CP087166
Organism Pseudomonas sp. B21-051

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LOY52_RS01340 Protein ID WP_258677882.1
Coordinates 304442..304756 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LOY52_RS01335 Protein ID WP_258677880.1
Coordinates 304152..304439 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY52_RS01310 (LOY52_01310) 299284..299745 - 462 WP_007964698.1 ATP-dependent zinc protease -
LOY52_RS01315 (LOY52_01315) 299980..300387 + 408 WP_098966686.1 RNA-binding S4 domain-containing protein -
LOY52_RS01320 (LOY52_01320) 300554..301357 - 804 WP_096796730.1 phosphatase PAP2 family protein -
LOY52_RS01325 (LOY52_01325) 301462..302364 + 903 WP_258677876.1 Hsp33 family molecular chaperone HslO -
LOY52_RS01330 (LOY52_01330) 302546..304087 + 1542 WP_258677878.1 phosphoenolpyruvate carboxykinase -
LOY52_RS01335 (LOY52_01335) 304152..304439 - 288 WP_258677880.1 NadS family protein Antitoxin
LOY52_RS01340 (LOY52_01340) 304442..304756 - 315 WP_258677882.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY52_RS01345 (LOY52_01345) 304868..305171 - 304 Protein_261 hypothetical protein -
LOY52_RS01350 (LOY52_01350) 305514..306656 - 1143 WP_258679815.1 hypothetical protein -
LOY52_RS01355 (LOY52_01355) 306739..307023 - 285 WP_202370848.1 hypothetical protein -
LOY52_RS01360 (LOY52_01360) 307326..307829 + 504 WP_258677883.1 polysaccharide deacetylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(42-100)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-86)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11847.71 Da        Isoelectric Point: 10.2227

>T224956 WP_258677882.1 NZ_CP087166:c304756-304442 [Pseudomonas sp. B21-051]
MIFIETRIFTRRVKELLDDDTYAAFQKQLVVSPSIGDVIEGTGGIRKTRIAARGHGKQGGARVIYYHFVSASQIGLLMIY
PKNEQHDLSSDERKALKVLIEKWR

Download         Length: 315 bp

>T224956 NZ_CP120639:c754458-754036 [Rhizobium sp. 32-5/1]
ATGAGACTACTCCTCGATACGAACGTTCTGTCGGAAGTTACGAAGCCTCGCCCCGTTGAAAGCGTCCTGAAGTGGCTCCA
CTGCCTGGACGAAGACCGGACATTCATCAGCATCATATCGATTGCTGAAATTCGCCGCGGTGTCGCGCTGATGGATGCTG
GGCGAAAGCGCGACGCCCTGGACGAATGGCTTATGTATGATCTGCCTCAACGCTTCGAAAACCGGATTATTCGGGTGGAA
GCGCCTGTCGCCTTGGCTTGGGGTGATCTCATGGCTCTTGCCAAGCGAAGTGGTCGCGGGCTCGCCTCCATGGACGGCTT
GATTGCAGCTACCGCCGTCGCTCACCAATTGACCCTTGCGACGCGCAACACCAAGGATTTCGCAGGTTTTGGAATAGACA
TCATTGACCCATGGGTGGACTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10746.37 Da        Isoelectric Point: 6.8814

>AT224956 WP_258677880.1 NZ_CP087166:c304439-304152 [Pseudomonas sp. B21-051]
MSKFFDELMESVQEMDEIVRGERTPSREFHVDALQVKEIRKATGLTQAKFAALIDVQLGTLRNWEQGRREPTGPAKALLK
AIHNDPVHVLIALAH

Download         Length: 288 bp

>AT224956 NZ_CP120639:c754721-754455 [Rhizobium sp. 32-5/1]
ATGCAAGCATCAACACACGAAGATATGAGCTGGACGGTCGCCGGAGCGAAGGCGAAGCTATCGGAAGTCATGGAGCGAGC
GCAGGTGTCGCCTCAGACGATTACTCGCAATGGAAAGCCAAGCGTGGTGGTTGTTTCTGCTGAAGAGTGGCAGAAGAAGA
TTGCGCGCCGCGGATCGCTGGCGGAGTTCTTGTTGGCATCGCCGCTGCGTGGCGCCGATCTGGATATTGAGCGACAACAC
GACGAGCCGCGCGACTTGTCACTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References