Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 165604..166118 Replicon plasmid P1
Accession NZ_CP086996
Organism Pseudosulfitobacter pseudonitzschiae strain SC1-109

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LOE07_RS20020 Protein ID WP_224556955.1
Coordinates 165604..165870 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LOE07_RS20025 Protein ID WP_224556953.1
Coordinates 165867..166118 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE07_RS20005 (LOE07_19990) 162832..163713 + 882 WP_224556958.1 zinc-binding dehydrogenase -
LOE07_RS20010 (LOE07_19995) 163931..164634 - 704 Protein_155 IS6 family transposase -
LOE07_RS20015 (LOE07_20000) 165076..165543 + 468 WP_224556957.1 hypothetical protein -
LOE07_RS20020 (LOE07_20005) 165604..165870 - 267 WP_224556955.1 Txe/YoeB family addiction module toxin Toxin
LOE07_RS20025 (LOE07_20010) 165867..166118 - 252 WP_224556953.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LOE07_RS20030 (LOE07_20015) 166750..167661 - 912 Protein_159 IS3 family transposase -
LOE07_RS20035 (LOE07_20020) 167662..168606 - 945 Protein_160 transposase -
LOE07_RS20040 (LOE07_20025) 168772..169263 + 492 WP_224557005.1 3-keto-5-aminohexanoate cleavage protein -
LOE07_RS20045 (LOE07_20030) 169505..169861 + 357 WP_224556951.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - fcl / gmd 1..281162 281162
- flank IS/Tn - - 166750..167577 827


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10465.78 Da        Isoelectric Point: 9.5014

>T224636 WP_224556955.1 NZ_CP086996:c165870-165604 [Pseudosulfitobacter pseudonitzschiae]
VKLVFSDQAWEDYQYWVNTNDKVRDRINELIKQCRRTPFKGTGKPEPLKGDLTGWWSRRISQEDRMVYRVSGTGDGQSLE
IAQLRFHY

Download         Length: 267 bp

>T224636 NZ_CP120374:c1629756-1629370 [Sinorhizobium garamanticum]
ATGGTCATCGATACGTCGGCCATCGTCGCGCTCGCATTCAATGAGCCGGAAGCGGAAACCTACGAACGGAAAGTCGTCGA
TGCTCCACGGCGCTTCATCTCCGCAGCGACAGTCCTTGAACTCGCAATCGTTATCGAAGCCCGCCTCGGCGAGGCAGGTG
CCGCAGAGCTCGACCTATGGCTCTACAAGGCGGGTGTCGAAATCGTCGCCGTCGACGCAGAACAGATCGCCGTAGCAAGG
CGGGCCTGGCGCAGCTACGGCAAAGGCCGACATCCGGCAGGTCTGAACTATGGGGACTGTTTCTCCTATGCGCTGGCCAA
AACGCGCAACGAACCGCTGCTTTTCAAAGGCGATGATTTTTCGCGCACCGACATAGAGGCTGCATGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9165.43 Da        Isoelectric Point: 6.4652

>AT224636 WP_224556953.1 NZ_CP086996:c166118-165867 [Pseudosulfitobacter pseudonitzschiae]
MDVMTYSDARAQLKGVMDRAIHDKQEVVVTRKKGESVVVVSLETWNAVNETLHLLSTPKNASRLRASIAQLDAGTGEVRE
LTE

Download         Length: 252 bp

>AT224636 NZ_CP120374:c1630010-1629756 [Sinorhizobium garamanticum]
ATGGCGCTCAGCATCAAAGATCTAGAGACGGAACGCCTTGCAAAGGCACTGGCCGAGAAAACCGGTGAAACCATTACCAT
GGCGACGCGGCGCGCACTGGAAGAGCGGCTGCGGCGTCTCGCAAACGCGGGAAATCGCGATGTTCTCCTCGAGGAGCTTG
CCGCCAGTCGTGGACGCTGGGGCAAGCTGCCGGTACTGGACAACCGCTCTGCTGACGAGATTTTGGAGTATGACGAAAAC
GGGGCTCCCAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References