Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 242080..242594 Replicon plasmid P2
Accession NZ_CP086988
Organism Pseudosulfitobacter pseudonitzschiae strain SC1-110

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LOE08_RS20785 Protein ID WP_224556955.1
Coordinates 242328..242594 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LOE08_RS20780 Protein ID WP_229943298.1
Coordinates 242080..242331 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE08_RS20760 (LOE08_20715) 238337..238693 - 357 WP_224556951.1 hypothetical protein -
LOE08_RS20765 (LOE08_20720) 238935..239426 - 492 WP_224557005.1 3-keto-5-aminohexanoate cleavage protein -
LOE08_RS20770 (LOE08_20725) 239592..240536 + 945 Protein_234 transposase -
LOE08_RS20775 (LOE08_20730) 240537..241448 + 912 Protein_235 IS3 family transposase -
LOE08_RS20780 (LOE08_20735) 242080..242331 + 252 WP_229943298.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LOE08_RS20785 (LOE08_20740) 242328..242594 + 267 WP_224556955.1 Txe/YoeB family addiction module toxin Toxin
LOE08_RS20790 (LOE08_20745) 242655..243473 - 819 WP_229940646.1 hypothetical protein -
LOE08_RS20795 (LOE08_20750) 243564..244267 + 704 Protein_239 IS6 family transposase -
LOE08_RS20800 (LOE08_20755) 244485..245366 - 882 WP_224556958.1 zinc-binding dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - gmd / fcl 1..281173 281173
- flank IS/Tn - - 240621..241448 827


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10465.78 Da        Isoelectric Point: 9.5014

>T224631 WP_224556955.1 NZ_CP086988:242328-242594 [Pseudosulfitobacter pseudonitzschiae]
VKLVFSDQAWEDYQYWVNTNDKVRDRINELIKQCRRTPFKGTGKPEPLKGDLTGWWSRRISQEDRMVYRVSGTGDGQSLE
IAQLRFHY

Download         Length: 267 bp

>T224631 NZ_CP120370:c2205259-2204984 [Sinorhizobium numidicum]
ATGAAGCTTGAGTGGTCGAGTAAAGCGGTGTCCGATCTCGGGCGCCTCTATGATTTCCTGGCGCTAGTAAATCGGCAAGC
CGCTGTCCGCACCGTCCAATCTTTGACAAGCGCTCCAACAAGCCTGCTTGAACAACCATGGATCGGCGAGCGGCTGGAGG
AGTTCAATCCCCGCGAGGTCCGCCGAATCGTCGTTGGCCATTACGAAATGCGCTATGAGATCAGGCAGTCAACGATCTAC
GTGCTGCGGCTTTGGCATACGCGTGAAGAGCGATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9151.40 Da        Isoelectric Point: 6.4641

>AT224631 WP_229943298.1 NZ_CP086988:242080-242331 [Pseudosulfitobacter pseudonitzschiae]
MDVMTYSDARAQLKGVMDRAIHDKQEVVVTRKKGESVVVVSLDTWNAVNETLHLLSTPKNASRLRASIAQLDAGTGEVRE
LTE

Download         Length: 252 bp

>AT224631 NZ_CP120370:c2205519-2205259 [Sinorhizobium numidicum]
ATGGAAACGAAGGTAGTGACAGCGCACGTGCCCCTGCCGCTCGCCGAAAAAGTCGATCAGATCGCGGCTCGACTTGAGCG
TTCGCGCGGTTGGATCGTGAAGCAAGCGCTGGCGGCCTGGATCGACCAGGAAGAGGAACGCCGGCGCATGACTCTGGAGG
CGCTCGCTGACGTGGACAGTGGCCGGGTGATTGACCATCAGTCCGTGCAGGCGTGGGCCGACAGTCTCGACAGCGACAAG
CCGCGGCCGCTACCGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References