Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 165612..166126 Replicon plasmid P3
Accession NZ_CP086982
Organism Pseudosulfitobacter pseudonitzschiae strain SC1-111

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LOE09_RS20970 Protein ID WP_224556955.1
Coordinates 165612..165878 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LOE09_RS20975 Protein ID WP_224556953.1
Coordinates 165875..166126 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE09_RS20955 (LOE09_20945) 162840..163721 + 882 WP_224556958.1 zinc-binding dehydrogenase -
LOE09_RS20960 (LOE09_20950) 163939..164642 - 704 Protein_156 IS6 family transposase -
LOE09_RS20965 (LOE09_20955) 164733..165551 + 819 WP_229940646.1 hypothetical protein -
LOE09_RS20970 (LOE09_20960) 165612..165878 - 267 WP_224556955.1 Txe/YoeB family addiction module toxin Toxin
LOE09_RS20975 (LOE09_20965) 165875..166126 - 252 WP_224556953.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LOE09_RS20980 (LOE09_20970) 166758..167669 - 912 Protein_160 IS3 family transposase -
LOE09_RS20985 (LOE09_20975) 167670..168614 - 945 Protein_161 transposase -
LOE09_RS20990 (LOE09_20980) 168780..169271 + 492 WP_224557005.1 3-keto-5-aminohexanoate cleavage protein -
LOE09_RS20995 (LOE09_20985) 169513..169869 + 357 WP_224556951.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - fcl / gmd 1..281177 281177
- flank IS/Tn - - 166758..167585 827


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10465.78 Da        Isoelectric Point: 9.5014

>T224627 WP_224556955.1 NZ_CP086982:c165878-165612 [Pseudosulfitobacter pseudonitzschiae]
VKLVFSDQAWEDYQYWVNTNDKVRDRINELIKQCRRTPFKGTGKPEPLKGDLTGWWSRRISQEDRMVYRVSGTGDGQSLE
IAQLRFHY

Download         Length: 267 bp

>T224627 NZ_CP120369:c179717-179295 [Sinorhizobium numidicum]
ATGATCGTGCTCGACACCAACGTCATATCCGAATTGTGGAAGGCCGAGCCGGACCGCACTGTGTTGGCCTGGATCGATGC
GCAGATGATTGAAACACTGTATTTGTCCGCGATTACGGTGGCCGAACTGCGTTTCGGCTTGGCGGCCATGCCGGCAGGCA
AGCGACGCACGATCTTTCAGAATCGCTTGGAAGGAGAGGTCTTGCCAGCCCTTGCAGGGCGCGTTCTTCCCTTCGACTTG
GACGCGTCGCGAAGTTATGCGGACCTGATGGCGCAAGCGAAAACGTCAGGCAAGGCCATCGGCAAGGCGGATGGCTATAT
CGCCGCAACGGCGGTTGCGCATGGCTTTATGGTTGCTACGCGCGATACCAGTCCGTTCGAGGCCGCTGGACTAGACATCA
TCAACCCCTGGGAGCCGGCATGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9165.43 Da        Isoelectric Point: 6.4652

>AT224627 WP_224556953.1 NZ_CP086982:c166126-165875 [Pseudosulfitobacter pseudonitzschiae]
MDVMTYSDARAQLKGVMDRAIHDKQEVVVTRKKGESVVVVSLETWNAVNETLHLLSTPKNASRLRASIAQLDAGTGEVRE
LTE

Download         Length: 252 bp

>AT224627 NZ_CP120369:c179971-179714 [Sinorhizobium numidicum]
ATGGCAAATGTGACCGTTAGGAACCTGCCCGACGAGGTGCACCGAGCGCTACGCGTACGAGCAGCCATGCATGGCCGCAG
CACCGAAGCCGAGATCCGCGACATCCTCGAAACGACTGTCCGGCCCCCGGAGCGGGTCAAACTCGGCTCTTTATTGGCGT
CTATTGCCCATGAAGCTGGAGGGCTAACGGATGCCGAAGCGGAGCATTTCAACCAGCTCCGTGACAAGACTCCTGCTGAA
CCGATGAGCTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References