Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 103767..104281 Replicon plasmid P3
Accession NZ_CP086966
Organism Pseudosulfitobacter pseudonitzschiae strain SC1-15

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LOE11_RS21110 Protein ID WP_224556955.1
Coordinates 104015..104281 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LOE11_RS21105 Protein ID WP_224556953.1
Coordinates 103767..104018 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE11_RS21085 (LOE11_21085) 100024..100380 - 357 WP_224556951.1 hypothetical protein -
LOE11_RS21090 (LOE11_21090) 100622..101113 - 492 WP_224557005.1 3-keto-5-aminohexanoate cleavage protein -
LOE11_RS21095 (LOE11_21095) 101279..102223 + 945 Protein_101 transposase -
LOE11_RS21100 (LOE11_21100) 102224..103135 + 912 Protein_102 IS3 family transposase -
LOE11_RS21105 (LOE11_21105) 103767..104018 + 252 WP_224556953.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LOE11_RS21110 (LOE11_21110) 104015..104281 + 267 WP_224556955.1 Txe/YoeB family addiction module toxin Toxin
LOE11_RS21115 (LOE11_21115) 104342..105160 - 819 WP_229940646.1 hypothetical protein -
LOE11_RS21120 (LOE11_21120) 105251..105954 + 704 Protein_106 IS6 family transposase -
LOE11_RS21125 (LOE11_21125) 106172..107053 - 882 WP_224556958.1 zinc-binding dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..149482 149482
- flank IS/Tn - - 102308..103135 827


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10465.78 Da        Isoelectric Point: 9.5014

>T224613 WP_224556955.1 NZ_CP086966:104015-104281 [Pseudosulfitobacter pseudonitzschiae]
VKLVFSDQAWEDYQYWVNTNDKVRDRINELIKQCRRTPFKGTGKPEPLKGDLTGWWSRRISQEDRMVYRVSGTGDGQSLE
IAQLRFHY

Download         Length: 267 bp

>T224613 NZ_CP120365:c2268977-2268573 [Sinorhizobium kummerowiae]
GTGATCTCCCATATTCTCGACACCAGCGCCGTCATCGCTTTGATCGGGCGCAAATCGGATGCATTGGTCACCCGTGTACT
CCATAGCCCTCAGGGCATTATCGGGCTCCCGTCGGTCGTCGCGTATGAACTCTATTTTGGAGCGCAGAAAAGCGCGAAGG
CCCAACACAATCTCGAAACCCTGCGTTTGTTGATGGCGGATTTTCCGATCCTCGACTTCGACCGGAACGATGCCTTTGTC
GCAGGCGAGATCCGGGCCGCCCTTGCCGCGAAGGGTACGCCCATCGGACCTTATGACGTGCTGATTGCGGGACAGGCCAA
AGCCCGTGGATTGACGCTCGTCACCAACAATGTCGGCGAGTTCAATAGGGTTGAGAACCTGCGCGTGGAGGATTGGTCGC
TCTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9165.43 Da        Isoelectric Point: 6.4652

>AT224613 WP_224556953.1 NZ_CP086966:103767-104018 [Pseudosulfitobacter pseudonitzschiae]
MDVMTYSDARAQLKGVMDRAIHDKQEVVVTRKKGESVVVVSLETWNAVNETLHLLSTPKNASRLRASIAQLDAGTGEVRE
LTE

Download         Length: 252 bp

>AT224613 NZ_CP120365:c2269234-2268974 [Sinorhizobium kummerowiae]
ATGCCCCATCTTGCACGGGTGTTCCAGTCCGGAAATTCGCAGGCCGTCCGCCTGCCTAAGGAATTCCGCTTCAACGTCGA
TCGCGTCGAAATCACGCAGGAAGGCGACGCGCTCATTCTCCGCCCGCACGTCGAGCAAGGCGAGCAGTGGTCATCGCTGA
AGGCGGCACTTGCCCGTGGCATGAGTGAAGACTTCATGATGTGCGGGCGCGAGCAGCCGGAACAGCAGGATCGGCCGGAA
CTCGACGCGGTATTTCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References