Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 115052..115566 Replicon plasmid P2
Accession NZ_CP086956
Organism Pseudosulfitobacter pseudonitzschiae strain SC1-27

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LOE13_RS20390 Protein ID WP_224556955.1
Coordinates 115300..115566 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LOE13_RS20385 Protein ID WP_224556953.1
Coordinates 115052..115303 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE13_RS20365 (LOE13_20360) 111309..111665 - 357 WP_224556951.1 hypothetical protein -
LOE13_RS20370 (LOE13_20365) 111907..112398 - 492 WP_224557005.1 3-keto-5-aminohexanoate cleavage protein -
LOE13_RS20375 (LOE13_20370) 112564..113508 + 945 Protein_112 transposase -
LOE13_RS20380 (LOE13_20375) 113509..114420 + 912 Protein_113 IS3 family transposase -
LOE13_RS20385 (LOE13_20380) 115052..115303 + 252 WP_224556953.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LOE13_RS20390 (LOE13_20385) 115300..115566 + 267 WP_224556955.1 Txe/YoeB family addiction module toxin Toxin
LOE13_RS20395 (LOE13_20390) 115627..116445 - 819 WP_229940646.1 hypothetical protein -
LOE13_RS20400 (LOE13_20395) 116536..117239 + 704 Protein_117 IS6 family transposase -
LOE13_RS20405 (LOE13_20400) 117457..118314 - 858 WP_229940775.1 zinc-binding dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..168034 168034
- flank IS/Tn - - 113593..114420 827


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10465.78 Da        Isoelectric Point: 9.5014

>T224605 WP_224556955.1 NZ_CP086956:115300-115566 [Pseudosulfitobacter pseudonitzschiae]
VKLVFSDQAWEDYQYWVNTNDKVRDRINELIKQCRRTPFKGTGKPEPLKGDLTGWWSRRISQEDRMVYRVSGTGDGQSLE
IAQLRFHY

Download         Length: 267 bp

>T224605 NZ_CP120364:921316-921600 [Sinorhizobium kummerowiae]
ATGGCGACTGAGCTGCCTTTCCGGCTCGCTCCTGCCGCCAAGGCCGATCTTCGGAAGATATGGCGCTACACGGCTCGCCG
CTGGTCTCTGGAACAGGCGGAGACCTACCAAGACCAGCTTTACACTGCATTTGAGGGACTGGCCGCAGGGACGAAGAAAG
GCCGCAATGTCGATGTGCGACCGGGTTATCTCAAATACCCGGCAGGATCGCACATCGTCTATTTTCGGGATCGCGGCGAC
CGGATCGACATCATCCGCATCCTGCATGGCCGGATGGATGCCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9165.43 Da        Isoelectric Point: 6.4652

>AT224605 WP_224556953.1 NZ_CP086956:115052-115303 [Pseudosulfitobacter pseudonitzschiae]
MDVMTYSDARAQLKGVMDRAIHDKQEVVVTRKKGESVVVVSLETWNAVNETLHLLSTPKNASRLRASIAQLDAGTGEVRE
LTE

Download         Length: 252 bp

>AT224605 NZ_CP120364:921078-921326 [Sinorhizobium kummerowiae]
ATGGCTGCTAGAAGCACATCTATTTCCCTTGGCGATCACTTCGCCGGTTTCATCGACAGCCAGGTGCAAACCGGCCGCTA
CGGCTCCGCCAGCGACGTTGTGCGGGCTGGACTTCGGCTTTTGGAAGAACACGAGGCGAAGGTAAGGGCGCTGGAAGCGG
CTTTGATCGAGGGCGAAGAATCCGGCGAGCCAGAGCCATTCGACAACGAAGCGTTCAAAGCCGAAATGCGCGCCGAATAT
GGCGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References