Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 92593..93107 Replicon plasmid P1
Accession NZ_CP086948
Organism Pseudosulfitobacter pseudonitzschiae strain SC1-28

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LOE14_RS19635 Protein ID WP_224556955.1
Coordinates 92841..93107 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LOE14_RS19630 Protein ID WP_224556953.1
Coordinates 92593..92844 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE14_RS19610 (LOE14_19620) 88850..89206 - 357 WP_224556951.1 hypothetical protein -
LOE14_RS19615 (LOE14_19625) 89448..89939 - 492 WP_224557005.1 3-keto-5-aminohexanoate cleavage protein -
LOE14_RS19620 (LOE14_19630) 90105..91049 + 945 Protein_88 transposase -
LOE14_RS19625 (LOE14_19635) 91050..91961 + 912 Protein_89 IS3 family transposase -
LOE14_RS19630 (LOE14_19640) 92593..92844 + 252 WP_224556953.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LOE14_RS19635 (LOE14_19645) 92841..93107 + 267 WP_224556955.1 Txe/YoeB family addiction module toxin Toxin
LOE14_RS19640 93168..93635 - 468 WP_224556957.1 hypothetical protein -
LOE14_RS19645 (LOE14_19655) 94077..94780 + 704 Protein_93 IS6 family transposase -
LOE14_RS19650 (LOE14_19660) 94998..95879 - 882 WP_224556958.1 zinc-binding dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - gmd / fcl 1..281180 281180
- flank IS/Tn - - 91134..91961 827


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10465.78 Da        Isoelectric Point: 9.5014

>T224598 WP_224556955.1 NZ_CP086948:92841-93107 [Pseudosulfitobacter pseudonitzschiae]
VKLVFSDQAWEDYQYWVNTNDKVRDRINELIKQCRRTPFKGTGKPEPLKGDLTGWWSRRISQEDRMVYRVSGTGDGQSLE
IAQLRFHY

Download         Length: 267 bp

>T224598 NZ_CP120360:c122475-122161 [Janibacter sp. DB-40]
GTGCGGGAGATCTGCCTCGTCAGGCTGGACAAGACCCGACCGGCGCTCGTCCTCACCCGGGAGACCGCACGTGGGGCCAT
GACGAAGGTGACGCTCGCCCCGATCACCACCACGATCAAGGGGCTGTCCAGCGAGGTCCGGGTGGGGCCGGCGAACGGTC
TCGATCAGGACTGCGCCGTCGCCCTCGACAACGTCGTCACCGTCCCCGTGGAGCGGCTCGGACGCACCGTCGGGTACTTG
TCGGCGGCCCAGGAGGACGAGCTGGCCCGGGCCGTGGTCCTGGCCTACGACCTGGACCTGCCGCTCAGCGGATGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9165.43 Da        Isoelectric Point: 6.4652

>AT224598 WP_224556953.1 NZ_CP086948:92593-92844 [Pseudosulfitobacter pseudonitzschiae]
MDVMTYSDARAQLKGVMDRAIHDKQEVVVTRKKGESVVVVSLETWNAVNETLHLLSTPKNASRLRASIAQLDAGTGEVRE
LTE

Download         Length: 252 bp

>AT224598 NZ_CP120360:c122713-122480 [Janibacter sp. DB-40]
ATGAGCATCCAGATCGCCGTTCGCCTCCCTGACGAGATGGTGGAGTTCCTCGACCGGGAGGTCGCCAGCGGGCGGGTGAC
CAGCCGCGCGGCGCTCGTGACCTCTGCGCTGGAGCGGGAGATGCGTCGGCTGGCCGCCGAGCACGACGTGGCTCTCCTGC
ACGAGAGGGGCACCGCCGACGACCTCGACGATCTGGTCACGTGGACGAGCACGCACGTGGGGCTCGGGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References