Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 92528..93042 Replicon plasmid P1
Accession NZ_CP086931
Organism Pseudosulfitobacter pseudonitzschiae strain SC1-30

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LOE16_RS19710 Protein ID WP_224556955.1
Coordinates 92776..93042 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LOE16_RS19705 Protein ID WP_224556953.1
Coordinates 92528..92779 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE16_RS19685 (LOE16_19675) 88785..89141 - 357 WP_224556951.1 hypothetical protein -
LOE16_RS19690 (LOE16_19680) 89383..89874 - 492 WP_224557005.1 3-keto-5-aminohexanoate cleavage protein -
LOE16_RS19695 (LOE16_19685) 90040..90984 + 945 Protein_88 transposase -
LOE16_RS19700 (LOE16_19690) 90985..91896 + 912 Protein_89 IS3 family transposase -
LOE16_RS19705 (LOE16_19695) 92528..92779 + 252 WP_224556953.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LOE16_RS19710 (LOE16_19700) 92776..93042 + 267 WP_224556955.1 Txe/YoeB family addiction module toxin Toxin
LOE16_RS19715 (LOE16_19705) 93103..93921 - 819 WP_229940646.1 hypothetical protein -
LOE16_RS19720 (LOE16_19710) 94012..94715 + 704 Protein_93 IS6 family transposase -
LOE16_RS19725 (LOE16_19715) 94933..95790 - 858 WP_229940775.1 zinc-binding dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..149480 149480
- flank IS/Tn - - 91069..91896 827


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10465.78 Da        Isoelectric Point: 9.5014

>T224585 WP_224556955.1 NZ_CP086931:92776-93042 [Pseudosulfitobacter pseudonitzschiae]
VKLVFSDQAWEDYQYWVNTNDKVRDRINELIKQCRRTPFKGTGKPEPLKGDLTGWWSRRISQEDRMVYRVSGTGDGQSLE
IAQLRFHY

Download         Length: 267 bp

>T224585 NZ_CP120350:14790-15122 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGGACAGAGGGGAAATCTGGCTCGTCTCACTGGATCCTACAGCCGGACATGAACAAAGCGGAAAACGTCCGGTACTTAT
CGTTTCTCCGGCATCATTTAATAAGTTCACCCGGTTACCCGTTGTCGTTCCCGTCACCAGCGGCGGAGACTTTGCCCGCA
CAGCCGGTTTTACCGTCTCCCTGGACGGCGCGGGAACAAAAACAACGGGTGTTATTCGCTGCGACCAGCCCAGAACGATT
GATATGGGTGCCCGGAATGGTAAGCGTCTGGAACGTATACCCGAAGCTGTCGTAAATGAAGTGCTGGCCCGACTGGAAGC
CATTCTGAGCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9165.43 Da        Isoelectric Point: 6.4652

>AT224585 WP_224556953.1 NZ_CP086931:92528-92779 [Pseudosulfitobacter pseudonitzschiae]
MDVMTYSDARAQLKGVMDRAIHDKQEVVVTRKKGESVVVVSLETWNAVNETLHLLSTPKNASRLRASIAQLDAGTGEVRE
LTE

Download         Length: 252 bp

>AT224585 NZ_CP120350:14532-14789 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGTATACCACTCGTCTGAAAAAGGTTGGCGGATCCGTCATGCTGGCGGTTCCTCCCGCCGTGTTGAAAACGCTGGCTCT
GTCGACAGACAGCGAAGTGGGAATGACCATTGATAATGGCTGCCTGATTATTGAACCCCAGAAACGGCCCCGTTATTCGC
TTGAGGAACTGCTGGCACAGTGCGATCCGCACGCCGAAATGAGCGATGAGGATAGGGAATGGATGGATGCGCCTGCAGTG
GGTAAGGAGATCCTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References