Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 92529..93043 Replicon plasmid P2
Accession NZ_CP086888
Organism Pseudosulfitobacter pseudonitzschiae strain SC1-67

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LOE21_RS20015 Protein ID WP_224556955.1
Coordinates 92777..93043 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LOE21_RS20010 Protein ID WP_224556953.1
Coordinates 92529..92780 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE21_RS19990 (LOE21_19990) 88786..89142 - 357 WP_224556951.1 hypothetical protein -
LOE21_RS19995 (LOE21_19995) 89384..89875 - 492 WP_224557005.1 3-keto-5-aminohexanoate cleavage protein -
LOE21_RS20000 (LOE21_20000) 90041..90985 + 945 Protein_88 transposase -
LOE21_RS20005 (LOE21_20005) 90986..91897 + 912 Protein_89 IS3 family transposase -
LOE21_RS20010 (LOE21_20010) 92529..92780 + 252 WP_224556953.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LOE21_RS20015 (LOE21_20015) 92777..93043 + 267 WP_224556955.1 Txe/YoeB family addiction module toxin Toxin
LOE21_RS20020 93104..93922 - 819 WP_229940646.1 hypothetical protein -
LOE21_RS20025 (LOE21_20025) 94013..94716 + 704 Protein_93 IS6 family transposase -
LOE21_RS20030 (LOE21_20030) 94934..95791 - 858 WP_229940775.1 zinc-binding dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..168033 168033
- flank IS/Tn - - 91070..91897 827


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10465.78 Da        Isoelectric Point: 9.5014

>T224551 WP_224556955.1 NZ_CP086888:92777-93043 [Pseudosulfitobacter pseudonitzschiae]
VKLVFSDQAWEDYQYWVNTNDKVRDRINELIKQCRRTPFKGTGKPEPLKGDLTGWWSRRISQEDRMVYRVSGTGDGQSLE
IAQLRFHY

Download         Length: 267 bp

>T224551 NZ_CP120345:3522063-3522281 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGTCTGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTACGGCGCTGTCAGACAATTGACACTCTGGAGCGCGT
CATTGAGAAAAATAAATATGAATTGTCCGACAATGAGCTGGCTGTATTTTACTCAGCTGCGGATCACCGTCTTGCAGAAT
TGACGATGAACAAACTCTACGACAAGATCCCCTCTTCAGTATGGAAATTCATTCGTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9165.43 Da        Isoelectric Point: 6.4652

>AT224551 WP_224556953.1 NZ_CP086888:92529-92780 [Pseudosulfitobacter pseudonitzschiae]
MDVMTYSDARAQLKGVMDRAIHDKQEVVVTRKKGESVVVVSLETWNAVNETLHLLSTPKNASRLRASIAQLDAGTGEVRE
LTE

Download         Length: 252 bp

>AT224551 NZ_CP120345:3521661-3522035 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGGACGAATACTCACCCAAAAGACATGATATAGCACAGCTTAAATTTCTTTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAACCATGGCTGGGTTAATGACCCGACCTCAGCAGTCAACCTGCAGCTCAATGAGCTGATAGAGC
ATATTGCAACTTTCGCGCTTAATTATAAAATTAAGTACAATGAAGACAATAAATTGATTGCGCAGATAGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTATGGTATTAATACGCAGGATTTGCAAAAATGGCGTAAATCGGGCAACCGCCT
GTTCCGTTGTTTCGTCAACGCCACCAGGGCTAATCCTGTTAGTTTGTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References