Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 119172..119686 Replicon plasmid P3
Accession NZ_CP086865
Organism Pseudosulfitobacter pseudonitzschiae strain SC33-17

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LOE29_RS21580 Protein ID WP_224556955.1
Coordinates 119420..119686 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LOE29_RS21575 Protein ID WP_224556953.1
Coordinates 119172..119423 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE29_RS21555 (LOE29_21545) 115429..115785 - 357 WP_224556951.1 hypothetical protein -
LOE29_RS21560 (LOE29_21550) 116027..116452 - 426 WP_229939140.1 3-keto-5-aminohexanoate cleavage protein -
LOE29_RS21565 (LOE29_21555) 116684..117628 + 945 Protein_115 transposase -
LOE29_RS21570 (LOE29_21560) 117629..118540 + 912 Protein_116 IS3 family transposase -
LOE29_RS21575 (LOE29_21565) 119172..119423 + 252 WP_224556953.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LOE29_RS21580 (LOE29_21570) 119420..119686 + 267 WP_224556955.1 Txe/YoeB family addiction module toxin Toxin
LOE29_RS21585 (LOE29_21575) 119747..120565 - 819 WP_229940646.1 hypothetical protein -
LOE29_RS21590 (LOE29_21580) 120656..121359 + 704 Protein_120 IS6 family transposase -
LOE29_RS21595 (LOE29_21585) 121577..122458 - 882 WP_224556958.1 zinc-binding dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - gmd / fcl 1..281175 281175
- flank IS/Tn - - 117713..118540 827


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10465.78 Da        Isoelectric Point: 9.5014

>T224532 WP_224556955.1 NZ_CP086865:119420-119686 [Pseudosulfitobacter pseudonitzschiae]
VKLVFSDQAWEDYQYWVNTNDKVRDRINELIKQCRRTPFKGTGKPEPLKGDLTGWWSRRISQEDRMVYRVSGTGDGQSLE
IAQLRFHY

Download         Length: 267 bp

>T224532 NZ_CP120342:c56687-56406 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGACCTATGAACTGGCTTTTGACCGTAGAGCACTGAAGGAATGGCAGAAACTCGGCCACACCATCCGTGAACAATTCAA
AAAGAAACTGGCAGAACGGCTGGAAAATCCACGCGTACCCGCAGCCCGGTTACATGGTCATGCTGATCGCTATAAAATCA
AACTTCGTGCATCTGGCTACAGACTTGTATATCAAGTCATTGATGAGAAAGTCGTTTTACTCGTTATTGCCGTTGGAAGA
AGGGAAAGCAGCGAAGTCTATCAGATCGCAGATTTGCGCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9165.43 Da        Isoelectric Point: 6.4652

>AT224532 WP_224556953.1 NZ_CP086865:119172-119423 [Pseudosulfitobacter pseudonitzschiae]
MDVMTYSDARAQLKGVMDRAIHDKQEVVVTRKKGESVVVVSLETWNAVNETLHLLSTPKNASRLRASIAQLDAGTGEVRE
LTE

Download         Length: 252 bp

>AT224532 NZ_CP120342:c56928-56677 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGAGCTATCAAATTCTGACAACCACAGCGGCCAGTATTACTGACCTGAAAAAAAATCCTATGGGAACCGTAGCTGAAGG
TGAAGGGGACGCTGTTGCGATCCTGAACCGAAACGAACCGGCGTTCTATTGCGTTCCACCAAAACTTTACGCCTACTATC
GGGAACTCGCTGAAGATGCTGAGTTAAACGCTGTTGCTGATGAGCGCATGAAAAACCCGGAAATTGTGAAGGTTAACCTG
GATGACCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References