Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 115046..115560 Replicon plasmid P1
Accession NZ_CP086833
Organism Pseudosulfitobacter pseudonitzschiae strain TC12-33

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LOE25_RS19590 Protein ID WP_224556955.1
Coordinates 115294..115560 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LOE25_RS19585 Protein ID WP_224556953.1
Coordinates 115046..115297 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE25_RS19565 (LOE25_19545) 111303..111659 - 357 WP_224556951.1 hypothetical protein -
LOE25_RS19570 (LOE25_19550) 111901..112392 - 492 WP_224557005.1 3-keto-5-aminohexanoate cleavage protein -
LOE25_RS19575 (LOE25_19555) 112558..113502 + 945 Protein_114 transposase -
LOE25_RS19580 (LOE25_19560) 113503..114414 + 912 Protein_115 IS3 family transposase -
LOE25_RS19585 (LOE25_19565) 115046..115297 + 252 WP_224556953.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LOE25_RS19590 (LOE25_19570) 115294..115560 + 267 WP_224556955.1 Txe/YoeB family addiction module toxin Toxin
LOE25_RS19595 115621..116439 - 819 WP_229940646.1 hypothetical protein -
LOE25_RS19600 (LOE25_19580) 116530..117233 + 704 Protein_119 IS6 family transposase -
LOE25_RS19605 (LOE25_19585) 117451..118332 - 882 WP_224556958.1 zinc-binding dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - gmd / fcl 1..281162 281162
- flank IS/Tn - - 113587..114414 827


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10465.78 Da        Isoelectric Point: 9.5014

>T224505 WP_224556955.1 NZ_CP086833:115294-115560 [Pseudosulfitobacter pseudonitzschiae]
VKLVFSDQAWEDYQYWVNTNDKVRDRINELIKQCRRTPFKGTGKPEPLKGDLTGWWSRRISQEDRMVYRVSGTGDGQSLE
IAQLRFHY

Download         Length: 267 bp

>T224505 NZ_CP120338:14790-15122 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGGACAGAGGGGAAATCTGGCTCGTCTCACTGGATCCTACAGCCGGACATGAACAAAGCGGAAAACGTCCGGTACTTAT
CGTTTCTCCGGCATCATTTAATAAGTTCACCCGGTTACCCGTTGTCGTTCCCGTCACCAGCGGCGGAGACTTTGCCCGCA
CAGCCGGTTTTACCGTCTCCCTGGACGGCGCGGGAACAAAAACAACGGGTGTTATTCGCTGCGACCAGCCCAGAACGATT
GATATGGGTGCCCGGAATGGTAAGCGTCTGGAACGTATACCCGAAGCTGTCGTAAATGAAGTGCTGGCCCGACTGGAAGC
CATTCTGAGCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9165.43 Da        Isoelectric Point: 6.4652

>AT224505 WP_224556953.1 NZ_CP086833:115046-115297 [Pseudosulfitobacter pseudonitzschiae]
MDVMTYSDARAQLKGVMDRAIHDKQEVVVTRKKGESVVVVSLETWNAVNETLHLLSTPKNASRLRASIAQLDAGTGEVRE
LTE

Download         Length: 252 bp

>AT224505 NZ_CP120338:14532-14789 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGTATACCACTCGTCTGAAAAAGGTTGGCGGATCCGTCATGCTGGCGGTTCCTCCCGCCGTGTTGAAAACGCTGGCTCT
GTCGACAGACAGCGAAGTGGGAATGACCATTGATAATGGCTGCCTGATTATTGAACCCCAGAAACGGCCCCGTTATTCGC
TTGAGGAACTGCTGGCACAGTGCGATCCGCACGCCGAAATGAGCGATGAGGATAGGGAATGGATGGATGCGCCTGCAGTG
GGTAAGGAGATCCTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References