Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 55706..56220 Replicon plasmid P4
Accession NZ_CP086820
Organism Pseudosulfitobacter pseudonitzschiae strain TC12-52

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LOE26_RS21960 Protein ID WP_224556955.1
Coordinates 55706..55972 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LOE26_RS21965 Protein ID WP_224556953.1
Coordinates 55969..56220 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE26_RS21945 (LOE26_21940) 52934..53815 + 882 WP_224556958.1 zinc-binding dehydrogenase -
LOE26_RS21950 (LOE26_21945) 54033..54736 - 704 Protein_54 IS6 family transposase -
LOE26_RS21955 55178..55645 + 468 WP_224556957.1 hypothetical protein -
LOE26_RS21960 (LOE26_21955) 55706..55972 - 267 WP_224556955.1 Txe/YoeB family addiction module toxin Toxin
LOE26_RS21965 (LOE26_21960) 55969..56220 - 252 WP_224556953.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LOE26_RS21970 (LOE26_21965) 56852..57763 - 912 Protein_58 IS3 family transposase -
LOE26_RS21975 (LOE26_21970) 57764..58708 - 945 Protein_59 transposase -
LOE26_RS21980 (LOE26_21975) 58874..59365 + 492 WP_224557005.1 3-keto-5-aminohexanoate cleavage protein -
LOE26_RS21985 (LOE26_21980) 59607..59963 + 357 WP_224556951.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - fcl / gmd 1..281176 281176
- flank IS/Tn - - 56852..57679 827


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10465.78 Da        Isoelectric Point: 9.5014

>T224495 WP_224556955.1 NZ_CP086820:c55972-55706 [Pseudosulfitobacter pseudonitzschiae]
VKLVFSDQAWEDYQYWVNTNDKVRDRINELIKQCRRTPFKGTGKPEPLKGDLTGWWSRRISQEDRMVYRVSGTGDGQSLE
IAQLRFHY

Download         Length: 267 bp

>T224495 NZ_CP120337:311879-312247 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGACCCTACAACTTATCTCAGCGGAAGAGATAATTCAGTTTCACGACAGGCTTCTCCGCGTTACGCCTGGTGTAACAGG
CATGCCTGATCCTGGCCGCGCGGAAGCGCTAATGTATCGGGTACTCAATCAAATCGAATATGAAGGGGTGACCGACGTGT
GGCTGCTGGCGGCAATGCATTTGCTCACTATATCCCGTGGGTATATCTTCAATGATGGTAACAAACGCACCGCCTTATTT
ATTACGCTGCTGTTTTTAAAGCGTAACGGGATCTCACTCGCTGCGAATCCGGATTTTGTCGATATGACAGTCGATGCGGC
GGCAGGGCGGCTTACGCTGGAACAAATTGCCGTTCGCTTACGTGCCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9165.43 Da        Isoelectric Point: 6.4652

>AT224495 WP_224556953.1 NZ_CP086820:c56220-55969 [Pseudosulfitobacter pseudonitzschiae]
MDVMTYSDARAQLKGVMDRAIHDKQEVVVTRKKGESVVVVSLETWNAVNETLHLLSTPKNASRLRASIAQLDAGTGEVRE
LTE

Download         Length: 252 bp

>AT224495 NZ_CP120337:311661-311882 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGCGTACGGTTAACTATAGCGAAGCGCGGCAAAATCTGGCCGAAGTCCTGGAAAGCGCGGTAACGGCGGGCCCTGTTAC
CATCACGCGTCGTGGGCATAAGTCCGCAGTGATCATCAGCGCCGAGGAGTTTGAGCGTTATCAGACGGCGCGAATGGATG
ATGAGTTTGCTGCCATTATGGCGGTTCATGGCAATGAGCTCAGGAAGCTGGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References