Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/YoeB-RelB |
Location | 14117..14631 | Replicon | plasmid P1 |
Accession | NZ_CP086799 | ||
Organism | Pseudosulfitobacter pseudonitzschiae strain TT37-47 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | - |
Locus tag | LOE37_RS19355 | Protein ID | WP_224557656.1 |
Coordinates | 14365..14631 (+) | Length | 89 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | A0A074T9H5 |
Locus tag | LOE37_RS19350 | Protein ID | WP_036743750.1 |
Coordinates | 14117..14368 (+) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LOE37_RS19325 (LOE37_19320) | 9639..10550 | - | 912 | WP_229940889.1 | branched-chain amino acid ABC transporter permease | - |
LOE37_RS19330 (LOE37_19325) | 10569..11750 | - | 1182 | WP_229940888.1 | ABC transporter substrate-binding protein | - |
LOE37_RS19335 (LOE37_19330) | 12239..12640 | + | 402 | WP_229941941.1 | AraC family transcriptional regulator ligand-binding domain-containing protein | - |
LOE37_RS19340 (LOE37_19335) | 12631..13152 | + | 522 | WP_229941939.1 | helix-turn-helix domain-containing protein | - |
LOE37_RS19345 (LOE37_19340) | 13324..14010 | + | 687 | WP_224557655.1 | helix-turn-helix transcriptional regulator | - |
LOE37_RS19350 (LOE37_19345) | 14117..14368 | + | 252 | WP_036743750.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
LOE37_RS19355 (LOE37_19350) | 14365..14631 | + | 267 | WP_224557656.1 | Txe/YoeB family addiction module toxin | Toxin |
LOE37_RS19360 (LOE37_19355) | 14874..15917 | - | 1044 | WP_224557657.1 | IS5 family transposase | - |
LOE37_RS19365 (LOE37_19360) | 15951..16142 | - | 192 | WP_224557658.1 | hypothetical protein | - |
LOE37_RS19370 (LOE37_19365) | 16785..17369 | - | 585 | WP_229941940.1 | ParA family protein | - |
LOE37_RS19375 (LOE37_19370) | 17567..18601 | - | 1035 | WP_151654626.1 | replication initiator protein A | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..37716 | 37716 | |
- | flank | IS/Tn | - | - | 14874..15917 | 1043 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 89 a.a. Molecular weight: 10381.70 Da Isoelectric Point: 8.9104
>T224478 WP_224557656.1 NZ_CP086799:14365-14631 [Pseudosulfitobacter pseudonitzschiae]
VKLVFSDQAWEDYQYWVSTNDKVRDRINELIKQCKRTPFKGSGLPEPLKGDLTGWWSRRISQEDRMVYRVSGTGDGQSLE
IAQLRFHY
VKLVFSDQAWEDYQYWVSTNDKVRDRINELIKQCKRTPFKGSGLPEPLKGDLTGWWSRRISQEDRMVYRVSGTGDGQSLE
IAQLRFHY
Download Length: 267 bp
>T224478 NZ_CP120334:28885-29367 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGGAAATAAGTGTTACTGCACCGGAGTTGCTAAACGAGGAACACTATCTTCAACAGTTTGATTGCGGGAATGATGTGCT
CAGTGACTGGCTTCGCCGCAGAGCGATGAAGAACCAATACCTCAATGCCTCCCGTACATTTGTTATCTGCCCTGAAGGCA
CAAAGCGAGTAGTGGGATATTACTCTATTGCGACGGGGTCTGTAAGTCATGCCAGTTTAGGTCGCAGTTTACGCCAGAAT
ATGCCCGATCCTGTTCCGGTTGTTTTGCTGGGACGTCTTGCTGTTGATGAGTGTACTCAAGGGCATAGTTTTGGAAAATG
GCTGCTTAATGATGCTGTAACACGGGTATCTAACCTGGCAGACCAGGTGGGTATTAAAGCGATCATGGTTCATGCTATTG
ATGAACAGGCGAAAACATTCTATGAATACTTTGGCTTTGTTCAGTCTCCCATTGCGCCAAATACATTGTTCTACAAGATT
TAA
ATGGAAATAAGTGTTACTGCACCGGAGTTGCTAAACGAGGAACACTATCTTCAACAGTTTGATTGCGGGAATGATGTGCT
CAGTGACTGGCTTCGCCGCAGAGCGATGAAGAACCAATACCTCAATGCCTCCCGTACATTTGTTATCTGCCCTGAAGGCA
CAAAGCGAGTAGTGGGATATTACTCTATTGCGACGGGGTCTGTAAGTCATGCCAGTTTAGGTCGCAGTTTACGCCAGAAT
ATGCCCGATCCTGTTCCGGTTGTTTTGCTGGGACGTCTTGCTGTTGATGAGTGTACTCAAGGGCATAGTTTTGGAAAATG
GCTGCTTAATGATGCTGTAACACGGGTATCTAACCTGGCAGACCAGGTGGGTATTAAAGCGATCATGGTTCATGCTATTG
ATGAACAGGCGAAAACATTCTATGAATACTTTGGCTTTGTTCAGTCTCCCATTGCGCCAAATACATTGTTCTACAAGATT
TAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9181.38 Da Isoelectric Point: 5.6864
>AT224478 WP_036743750.1 NZ_CP086799:14117-14368 [Pseudosulfitobacter pseudonitzschiae]
MDVMTYSDARAQLKGVMDRAIHDKQEVVVTRKKGESVVVVSLDTWNAVNETLHLLSTPKNASRLRASIAQLDAGTGEERE
LTE
MDVMTYSDARAQLKGVMDRAIHDKQEVVVTRKKGESVVVVSLDTWNAVNETLHLLSTPKNASRLRASIAQLDAGTGEERE
LTE
Download Length: 252 bp
>AT224478 NZ_CP120334:28610-28894 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGCAAACTACAATCCGCAAATCTGTGCGTAATAAACAAATAAATATACGGGCTACTGATGAGGAACGTGCTGTGATTGA
TTATGCAGCGAGCCTGGTCAGTAAAAACCGTACCGACTTCATCATAGAAAAGGCTGTGAGCGAGGCCCAGAATATCATTC
TGGATCAACGCGTTTTTGTTCTGGATGATGCCCGCTATCAGGCTTTTATTAAACAACTTGAAGCTCCTGTACAGAATACT
GAAGGTCGTCAGCGCCTGATGGATGTGAAACCTGAATGGAAATAA
ATGCAAACTACAATCCGCAAATCTGTGCGTAATAAACAAATAAATATACGGGCTACTGATGAGGAACGTGCTGTGATTGA
TTATGCAGCGAGCCTGGTCAGTAAAAACCGTACCGACTTCATCATAGAAAAGGCTGTGAGCGAGGCCCAGAATATCATTC
TGGATCAACGCGTTTTTGTTCTGGATGATGCCCGCTATCAGGCTTTTATTAAACAACTTGAAGCTCCTGTACAGAATACT
GAAGGTCGTCAGCGCCTGATGGATGTGAAACCTGAATGGAAATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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