Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | ldrD-ohsC/Ldr(toxin) |
Location | 1359940..1360161 | Replicon | chromosome |
Accession | NC_009801 | ||
Organism | Escherichia coli E24377A |
Toxin (Protein)
Gene name | ldrD | Uniprot ID | S1PGT3 |
Locus tag | ECE24377A_RS08355 | Protein ID | WP_000170954.1 |
Coordinates | 1359940..1360047 (-) | Length | 36 a.a. |
Antitoxin (RNA)
Gene name | ohsC | ||
Locus tag | - | ||
Coordinates | 1360095..1360161 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ECE24377A_RS08330 | 1355784..1356866 | + | 1083 | WP_000804726.1 | peptide chain release factor 1 | - |
ECE24377A_RS08335 | 1356866..1357699 | + | 834 | WP_000456461.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
ECE24377A_RS08340 | 1357696..1358088 | + | 393 | WP_000200392.1 | invasion regulator SirB2 | - |
ECE24377A_RS08345 | 1358092..1358901 | + | 810 | WP_001257044.1 | invasion regulator SirB1 | - |
ECE24377A_RS08350 | 1358937..1359791 | + | 855 | WP_000811065.1 | 3-deoxy-8-phosphooctulonate synthase | - |
ECE24377A_RS08355 | 1359940..1360047 | - | 108 | WP_000170954.1 | type I toxin-antitoxin system toxin Ldr family protein | Toxin |
- | 1360095..1360161 | + | 67 | NuclAT_14 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_14 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_14 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_14 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_16 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_16 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_16 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_16 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_18 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_18 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_18 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_18 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_20 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_20 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_20 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_20 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_22 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_22 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_22 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_22 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_24 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_24 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_24 | - | Antitoxin |
- | 1360095..1360161 | + | 67 | NuclAT_24 | - | Antitoxin |
- | 1360097..1360160 | + | 64 | NuclAT_27 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_27 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_27 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_27 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_29 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_29 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_29 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_29 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_31 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_31 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_31 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_31 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_33 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_33 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_33 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_33 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_35 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_35 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_35 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_35 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_37 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_37 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_37 | - | - |
- | 1360097..1360160 | + | 64 | NuclAT_37 | - | - |
ECE24377A_RS29975 | 1360475..1360582 | - | 108 | WP_000170926.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
- | 1360635..1360696 | + | 62 | NuclAT_26 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_26 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_26 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_26 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_28 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_28 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_28 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_28 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_30 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_30 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_30 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_30 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_32 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_32 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_32 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_32 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_34 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_34 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_34 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_34 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_36 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_36 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_36 | - | - |
- | 1360635..1360696 | + | 62 | NuclAT_36 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_15 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_15 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_15 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_15 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_17 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_17 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_17 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_17 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_19 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_19 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_19 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_19 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_21 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_21 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_21 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_21 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_23 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_23 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_23 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_23 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_25 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_25 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_25 | - | - |
- | 1360635..1360697 | + | 63 | NuclAT_25 | - | - |
- | 1360635..1360698 | + | 64 | NuclAT_38 | - | - |
- | 1360635..1360698 | + | 64 | NuclAT_38 | - | - |
- | 1360635..1360698 | + | 64 | NuclAT_38 | - | - |
- | 1360635..1360698 | + | 64 | NuclAT_38 | - | - |
- | 1360635..1360698 | + | 64 | NuclAT_39 | - | - |
- | 1360635..1360698 | + | 64 | NuclAT_39 | - | - |
- | 1360635..1360698 | + | 64 | NuclAT_39 | - | - |
- | 1360635..1360698 | + | 64 | NuclAT_39 | - | - |
- | 1360635..1360698 | + | 64 | NuclAT_40 | - | - |
- | 1360635..1360698 | + | 64 | NuclAT_40 | - | - |
- | 1360635..1360698 | + | 64 | NuclAT_40 | - | - |
- | 1360635..1360698 | + | 64 | NuclAT_40 | - | - |
ECE24377A_RS08365 | 1360988..1362088 | - | 1101 | WP_001295620.1 | sodium-potassium/proton antiporter ChaA | - |
ECE24377A_RS08370 | 1362358..1362588 | + | 231 | WP_001146442.1 | putative cation transport regulator ChaB | - |
ECE24377A_RS08375 | 1362746..1363441 | + | 696 | WP_001295621.1 | glutathione-specific gamma-glutamylcyclotransferase | - |
ECE24377A_RS08380 | 1363485..1363838 | - | 354 | WP_001169669.1 | DsrE/F sulfur relay family protein YchN | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 3983.80 Da Isoelectric Point: 11.4779
>T22445 WP_000170954.1 NC_009801:c1360047-1359940 [Escherichia coli O139:H28 str. E24377A]
MTLAQFAMIFWHDLAAPILAGIITAAIVGWWRNRK
MTLAQFAMIFWHDLAAPILAGIITAAIVGWWRNRK
Download Length: 108 bp
>T22445 NC_009801:c1360047-1359940 [Escherichia coli O139:H28 str. E24377A]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 67 bp
>AT22445 NC_009801:1360095-1360161 [Escherichia coli O139:H28 str. E24377A]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCTC
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCTC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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