Detailed information of TA system TA224398

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 1197346..1197540
• Replicon: chromosome
• Accession: NZ_CP086726
• Organism: Enterococcus faecalis strain E533

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: LM507_RS05690
• Protein ID: WP_015543884.1
• Coordinates: 1197346..1197441 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	1197476..1197540 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LM507_RS05670	1192524..1193639	+	1116	WP_081115739.1	FAD-dependent oxidoreductase	-
LM507_RS05675	1193707..1194861	-	1155	WP_010819729.1	mannitol-1-phosphate 5-dehydrogenase	-
LM507_RS05680	1194876..1195313	-	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
LM507_RS05685	1195328..1197100	-	1773	WP_010819728.1	PTS mannitol-specific transporter subunit IIBC	-
LM507_RS05690	1197346..1197441	+	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	1197476..1197540	-	65	-	-	Antitoxin
LM507_RS05695	1197698..1198132	-	435	WP_010711967.1	PTS sugar transporter subunit IIA	-
LM507_RS05700	1198143..1200176	-	2034	WP_010819727.1	BglG family transcription antiterminator	-
LM507_RS05705	1200167..1201915	-	1749	WP_010819726.1	PTS transporter subunit EIIC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T224398 WP_015543884.1 NZ_CP086726:1197346-1197441 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T224398 NZ_CP120322:532743-533234 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGATCTCCACCCCTGAGCCGCTTCATGCCGGACATATTCTTACTCCGTTTTGCTGCGGTGTGGATTCTATAGATAACTG
GCTGAAACAGCGGGCGATGAAAAATCAGACCACTGGCGCGTCCCGTACCTTTGTGTGTTGTGGCAGCGATTCGAACGTAC
TGGCCTATTACTCGCTGGCGTCCAGCGCGGTCACGACGAATACCTCCCCCGGTCGCTTTCGTCGCAATATGCCTGACCCG
ATTCCGGTTGTGGTATTGGGGCGTCTGGCGGTGGATAAATCGCTTCATGGGCAGGGCGTCGCTCGGGCGCTGGTACGCGA
CGCAGGGCTGCGGGTTATTCAGGTGGCGGAGACTATCGGCATTCGTGGGATGCTGGTTCACGCCCTGTCGGATGAAGCGC
GGGAATTTTATCAGCGGGTGGGGTTTGTACCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTGTTTAA

Antitoxin

Nucleotide

• Length: 65 bp

>AT224398 NZ_CP086726:c1197540-1197476 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGCAGTAGGGTGTCTTTTTTT

Structures

Antitoxin