Detailed information of TA system TA224289

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 1121670..1121832
• Replicon: chromosome
• Accession: NZ_CP086659
• Organism: Staphylococcus capitis strain XZ03

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A507SQ11
• Locus tag: LN243_RS05605
• Protein ID: WP_030063529.1
• Coordinates: 1121670..1121774 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	1121802..1121832 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LN243_RS05595	1117602..1120541	+	2940	WP_023350052.1	AAA family ATPase	-
LN243_RS05600	1120538..1121479	+	942	WP_002434737.1	3'-5' exoribonuclease YhaM	-
LN243_RS05605	1121670..1121774	+	105	WP_030063529.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	1121802..1121832	+	31	-	-	Antitoxin
LN243_RS05610	1121929..1122930	-	1002	WP_023350053.1	peptidylprolyl isomerase	-
LN243_RS05615	1123132..1123701	-	570	WP_002434864.1	DUF3267 domain-containing protein	-
LN243_RS05620	1123893..1124264	-	372	WP_002434824.1	YtxH domain-containing protein	-
LN243_RS05625	1124342..1124767	-	426	WP_002434751.1	HIT family protein	-
LN243_RS05630	1124900..1125640	+	741	WP_002453567.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3963.74 Da
• Isoelectric Point: 10.7588

>T224289 WP_030063529.1 NZ_CP086659:1121670-1121774 [Staphylococcus capitis]
MLFDIFVHIMATATSGCIVALFAHWLRTRNDKRK

Nucleotide

• Length: 105 bp

>T224289 NZ_CP119981:28886-29368 [Salmonella enterica]
ATGGAAATAAGTGTTACTGCACCGGAGTTGCTAAACGAGGAACACTATCTTCAACAGTTTGATTGCGGGAATGATGTGCT
CAGTGACTGGCTTCGCCGCAGAGCGATGAAGAACCAATACCTCAATGCCTCCCGTACATTTGTTATCTGCCCTGAAGGCA
CAAAGCGAGTAGTGGGATATTACTCTATTGCGACGGGGTCTGTAAGTCATGCCAGTTTAGGTCGCAGTTTACGCCAGAAT
ATGCCCGATCCTGTTCCGGTTGTTTTGCTGGGACGTCTTGCTGTTGATGAGTGTACTCAAGGGCATAGTTTTGGAAAATG
GCTGCTTAATGATGCTGTAACACGGGTATCTAACCTGGCAGACCAGGTGGGTATTAAAGCGATCATGGTTCATGCTATTG
ATGAACAGGCGAAAACATTCTATGAATACTTTGGCTTTGTTCAGTCTCCCATTGCGCCAAATACATTGTTCTACAAGATT
TAA

Antitoxin

Nucleotide

• Length: 31 bp

>AT224289 NZ_CP086659:1121802-1121832 [Staphylococcus capitis]
AAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A507SQ11

Antitoxin