Detailed information of TA system TA223947

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 350999..351193
• Replicon: chromosome
• Accession: NZ_CP086592
• Organism: Enterococcus faecalis strain Fac74

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: LNB41_RS01810
• Protein ID: WP_015543884.1
• Coordinates: 351098..351193 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	350999..351063 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LNB41_RS01795	346624..348372	+	1749	WP_010819726.1	PTS transporter subunit EIIC	-
LNB41_RS01800	348363..350396	+	2034	WP_010819727.1	BglG family transcription antiterminator	-
LNB41_RS01805	350407..350841	+	435	WP_010711967.1	PTS sugar transporter subunit IIA	-
-	350999..351063	+	65	-	-	Antitoxin
LNB41_RS01810	351098..351193	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
LNB41_RS01815	351439..353211	+	1773	WP_010819728.1	PTS mannitol-specific transporter subunit IIBC	-
LNB41_RS01820	353226..353663	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
LNB41_RS01825	353678..354832	+	1155	WP_010819729.1	mannitol-1-phosphate 5-dehydrogenase	-
LNB41_RS01830	354900..356015	-	1116	WP_081115739.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T223947 WP_015543884.1 NZ_CP086592:c351193-351098 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T223947 NZ_CP119408:c4604831-4604298 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATATGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin

Nucleotide

• Length: 65 bp

>AT223947 NZ_CP086592:350999-351063 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGCAGTAGGGTGTCTTTTTTT

Structures

Antitoxin