Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2449098..2449282 Replicon chromosome
Accession NZ_CP086574
Organism Staphylococcus argenteus strain RIVM_M046968

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag LK342_RS11835 Protein ID WP_047527328.1
Coordinates 2449175..2449282 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2449098..2449158 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LK342_RS11825 (LK342_11825) 2444952..2446685 - 1734 WP_047431349.1 ABC transporter ATP-binding protein -
LK342_RS11830 (LK342_11830) 2446710..2448473 - 1764 WP_047527326.1 ABC transporter ATP-binding protein -
- 2449098..2449158 + 61 - - Antitoxin
LK342_RS11835 (LK342_11835) 2449175..2449282 - 108 WP_047527328.1 type I toxin-antitoxin system Fst family toxin Toxin
LK342_RS11840 (LK342_11840) 2449417..2449803 - 387 WP_047527330.1 flippase GtxA -
LK342_RS11845 (LK342_11845) 2450070..2451212 + 1143 WP_047527332.1 glycerate kinase -
LK342_RS11850 (LK342_11850) 2451271..2451930 + 660 WP_000831306.1 membrane protein -
LK342_RS11855 (LK342_11855) 2452115..2453326 + 1212 WP_047527334.1 multidrug effflux MFS transporter -
LK342_RS11860 (LK342_11860) 2453442..2453921 - 480 WP_047527336.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T223944 WP_047527328.1 NZ_CP086574:c2449282-2449175 [Staphylococcus argenteus]
MFNLLIDIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T223944 NZ_CP119408:1914499-1914601 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 61 bp

>AT223944 NZ_CP086574:2449098-2449158 [Staphylococcus argenteus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References