223939

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1839891..1840071 Replicon chromosome
Accession NZ_CP086574
Organism Staphylococcus argenteus strain RIVM_M046968

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag LK342_RS08535 Protein ID WP_001801861.1
Coordinates 1839891..1839986 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1840014..1840071 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LK342_RS08505 (LK342_08505) 1835920..1836546 + 627 WP_047526911.1 hypothetical protein -
LK342_RS08510 (LK342_08510) 1836587..1836928 + 342 WP_047526913.1 DUF3969 family protein -
LK342_RS08515 (LK342_08515) 1837029..1837601 + 573 WP_047526915.1 hypothetical protein -
LK342_RS08520 (LK342_08520) 1837799..1838426 - 628 Protein_1675 ImmA/IrrE family metallo-endopeptidase -
LK342_RS08525 (LK342_08525) 1838541..1838987 - 447 WP_031787841.1 DUF1433 domain-containing protein -
LK342_RS08530 (LK342_08530) 1839109..1839366 - 258 WP_047526919.1 IS3 family transposase -
LK342_RS08535 (LK342_08535) 1839891..1839986 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1840014..1840071 - 58 - - Antitoxin
LK342_RS08540 (LK342_08540) 1840109..1840210 + 102 WP_047526922.1 hypothetical protein -
LK342_RS08545 (LK342_08545) 1840345..1840791 - 447 WP_047526923.1 DUF1433 domain-containing protein -
LK342_RS08550 (LK342_08550) 1840791..1841234 - 444 WP_047526925.1 DUF1433 domain-containing protein -
LK342_RS08555 (LK342_08555) 1841234..1841677 - 444 WP_047526927.1 DUF1433 domain-containing protein -
LK342_RS08560 (LK342_08560) 1842304..1843524 - 1221 WP_047526928.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T223939 WP_001801861.1 NZ_CP086574:1839891-1839986 [Staphylococcus argenteus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T223939 NZ_CP119404:c4217959-4217786 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 58 bp

>AT223939 NZ_CP086574:c1840071-1840014 [Staphylococcus argenteus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References