Detailed information of TA system TA223933

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2371438..2371622
• Replicon: chromosome
• Accession: NZ_CP086572
• Organism: Staphylococcus argenteus strain RIVM_M036020

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: LK336_RS11320
• Protein ID: WP_000482653.1
• Coordinates: 2371438..2371545 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2371562..2371622 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LK336_RS11295	2366799..2367278	+	480	WP_031787190.1	GyrI-like domain-containing protein	-
LK336_RS11300	2367394..2368605	-	1212	WP_031787189.1	multidrug effflux MFS transporter	-
LK336_RS11305	2368790..2369449	-	660	WP_000831306.1	membrane protein	-
LK336_RS11310	2369508..2370650	-	1143	WP_031787188.1	glycerate kinase	-
LK336_RS11315	2370918..2371304	+	387	WP_000779346.1	flippase GtxA	-
LK336_RS11320	2371438..2371545	+	108	WP_000482653.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2371562..2371622	-	61	-	-	Antitoxin
LK336_RS11325	2372249..2374012	+	1764	WP_031787187.1	ABC transporter ATP-binding protein	-
LK336_RS11330	2374037..2375770	+	1734	WP_031787186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4025.81 Da
• Isoelectric Point: 11.0582

>T223933 WP_000482653.1 NZ_CP086572:2371438-2371545 [Staphylococcus argenteus]
MFNLLINIMTTAISGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T223933 NZ_CP119404:2640276-2640383 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin

Nucleotide

• Length: 61 bp

>AT223933 NZ_CP086572:c2371622-2371562 [Staphylococcus argenteus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Antitoxin