Detailed information of TA system TA223922

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2327804..2327988
• Replicon: chromosome
• Accession: NZ_CP086570
• Organism: Staphylococcus argenteus strain RIVM_M020832

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: LK341_RS11000
• Protein ID: WP_000482653.1
• Coordinates: 2327804..2327911 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2327928..2327988 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LK341_RS10975	2323165..2323644	+	480	WP_031787190.1	GyrI-like domain-containing protein	-
LK341_RS10980	2323760..2324971	-	1212	WP_031787189.1	multidrug effflux MFS transporter	-
LK341_RS10985	2325156..2325815	-	660	WP_000831306.1	membrane protein	-
LK341_RS10990	2325874..2327016	-	1143	WP_031787188.1	glycerate kinase	-
LK341_RS10995	2327284..2327670	+	387	WP_000779346.1	flippase GtxA	-
LK341_RS11000	2327804..2327911	+	108	WP_000482653.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2327928..2327988	-	61	-	-	Antitoxin
LK341_RS11005	2328615..2330378	+	1764	WP_031787187.1	ABC transporter ATP-binding protein	-
LK341_RS11010	2330403..2332136	+	1734	WP_031787186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4025.81 Da
• Isoelectric Point: 11.0582

>T223922 WP_000482653.1 NZ_CP086570:2327804-2327911 [Staphylococcus argenteus]
MFNLLINIMTTAISGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T223922 NZ_CP119403:c8520-8140 [Escherichia coli]
ATGAGGCATATATCACCGGAAGAACTTATTGCGCTTCATGATGCGAATATAAACCGCTACGGCGGCCTGCCGGGAATGTC
AGATCCGGGTAGGGCAGAGGCCATTATCGGGAGAGTTCAGGCCAGAGTTGCCTACGAAGAGATCACCGACCTTTTCGAAG
TCTCCGCCACCTACCTGGTGGCTACAGCGAGAGGGCATATATTCAATGATGCCAATAAGCGTACCGCGCTAAACAGTGCG
CTGCTATTTCTACGCCGTAATGGGGTGCAGGTATTTGATTCACCTGAACTGGCAGACCTTACTGTAGGCGCTGCGACTGG
CGAGATATCTGTATCTTCTGTCGCCGCCACGTTACGTAGATTGTATGGTTCTGCGGAGTAG

Antitoxin

Nucleotide

• Length: 61 bp

>AT223922 NZ_CP086570:c2327988-2327928 [Staphylococcus argenteus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Antitoxin