Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2564123..2564307 Replicon chromosome
Accession NC_009782
Organism Staphylococcus aureus subsp. aureus Mu3

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag SAHV_RS13120 Protein ID WP_000482652.1
Coordinates 2564200..2564307 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2564123..2564183 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAHV_RS13095 2559578..2559745 - 168 Protein_2492 hypothetical protein -
SAHV_RS13105 2559976..2561709 - 1734 WP_000486487.1 ABC transporter ATP-binding protein/permease -
SAHV_RS13110 2561734..2563497 - 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
- 2564123..2564183 + 61 - - Antitoxin
SAHV_RS13120 2564200..2564307 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
SAHV_RS13125 2564441..2564827 - 387 WP_000779360.1 flippase GtxA -
SAHV_RS13130 2565095..2566237 + 1143 WP_001176863.1 glycerate kinase -
SAHV_RS13135 2566297..2566956 + 660 WP_000831298.1 membrane protein -
SAHV_RS13140 2567138..2568349 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
SAHV_RS13145 2568472..2568945 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T22388 WP_000482652.1 NC_009782:c2564307-2564200 [Staphylococcus aureus subsp. aureus Mu3]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T22388 NC_009782:c2564307-2564200 [Staphylococcus aureus subsp. aureus Mu3]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT22388 NC_009782:2564123-2564183 [Staphylococcus aureus subsp. aureus Mu3]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References