Detailed information of TA system TA223864

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 309002..309196
• Replicon: chromosome
• Accession: NZ_CP086564
• Organism: Enterococcus faecalis strain E512-TC1

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: LM511_RS01565
• Protein ID: WP_015543884.1
• Coordinates: 309101..309196 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	309002..309066 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LM511_RS01550	304620..306362	+	1743	WP_014524947.1	PTS transporter subunit EIIC	-
LM511_RS01555	306353..308386	+	2034	WP_002361171.1	PRD domain-containing protein	-
LM511_RS01560	308397..308831	+	435	WP_002358391.1	PTS sugar transporter subunit IIA	-
-	309002..309066	+	65	-	-	Antitoxin
LM511_RS01565	309101..309196	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
LM511_RS01570	309442..311214	+	1773	WP_002391520.1	PTS mannitol-specific transporter subunit IIBC	-
LM511_RS01575	311229..311666	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
LM511_RS01580	311681..312835	+	1155	WP_002413493.1	mannitol-1-phosphate 5-dehydrogenase	-
LM511_RS01585	312904..314019	-	1116	WP_002413492.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T223864 WP_015543884.1 NZ_CP086564:c309196-309101 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T223864 NZ_CP119368:4838615-4839190 [Pseudomonas sp. CBSPCGW29]
ATGGACATCGAAAAACTCAAGGGCCGCCTCGACTTCCTGCGCGAAGCGGAAAAACTCAAGGACGTGCTCAGAAGCGCGCA
CACCTCTTCCGGCCGCACCGAAAGCACCGCGGAACACAGCTGGCGCCTGTGCCTGATGGCAATTACCTTCGGGGATGAAC
TGGCCGGCCTCGACCTGCTGAAAATCCTCAAGATGTGCGTAATCCACGACCTGGGAGAGGCCCTCCACGGCGACATCCCG
GCGGTCCAGCAAGCGCAGTTCCCCAACAAGAGCCAGCAAGAACACGACGACCTGCTGTTGCTGACCCGAGCACTGGATGA
GCCGTTGCGGGTCGAGATTCTGGCCCTGTGGGACGACTACGAAAACGCCCGGTCCGCCGAGGCCAAGGCAGTCAAAGCCC
TGGACAAACTGGAGACCCTGCTGCAACACAACCAGGGCCTGAACCCGCCCGACTTCGACTACGCCTTCAATCTGGCCTAT
GGCAAGAAACACACCAGCGCCGAGCCGATTTTCCAGACACTGCGCGAGATCATCGACCAGGATACAGAAGCAAAAATCCA
GACTCCCAACCGGTAG

Antitoxin

Nucleotide

• Length: 65 bp

>AT223864 NZ_CP086564:309002-309066 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Structures

Antitoxin