Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2277790..2278006 Replicon chromosome
Accession NC_009782
Organism Staphylococcus aureus subsp. aureus Mu3

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SAHV_RS11605 Protein ID WP_001802298.1
Coordinates 2277902..2278006 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2277790..2277845 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAHV_RS11585 2273996..2274661 - 666 WP_001024095.1 SDR family oxidoreductase -
SAHV_RS11590 2274813..2275133 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SAHV_RS11595 2275135..2276112 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
SAHV_RS11600 2276378..2277469 + 1092 WP_000495669.1 hypothetical protein -
- 2277790..2277845 + 56 - - Antitoxin
SAHV_RS11605 2277902..2278006 - 105 WP_001802298.1 hypothetical protein Toxin
SAHV_RS15570 2278523..2278693 + 171 WP_001792292.1 transposase -
SAHV_RS15220 2278686..2278844 + 159 WP_001792784.1 hypothetical protein -
SAHV_RS11610 2279502..2280359 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
SAHV_RS11615 2280427..2281209 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T22385 WP_001802298.1 NC_009782:c2278006-2277902 [Staphylococcus aureus subsp. aureus Mu3]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T22385 NC_009782:c2278006-2277902 [Staphylococcus aureus subsp. aureus Mu3]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT22385 NC_009782:2277790-2277845 [Staphylococcus aureus subsp. aureus Mu3]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9


Antitoxin

Download structure file

References