Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2982373..2982641 Replicon chromosome
Accession NZ_CP086558
Organism Enterococcus faecalis strain E512

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag LM505_RS14685 Protein ID WP_080113450.1
Coordinates 2982373..2982537 (+) Length 55 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2982446..2982641 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LM505_RS14660 2977828..2978460 - 633 WP_002358972.1 RloB family protein -
LM505_RS14665 2978469..2979569 - 1101 WP_229022098.1 ATP-binding protein -
LM505_RS14670 2979569..2979763 - 195 WP_229022099.1 hypothetical protein -
LM505_RS14675 2980225..2981841 + 1617 WP_010820356.1 phosphatase PAP2/LCP family protein -
LM505_RS14680 2982149..2982253 + 105 WP_023894767.1 putative holin-like toxin -
LM505_RS14685 2982373..2982537 + 165 WP_080113450.1 putative holin-like toxin Toxin
- 2982446..2982641 - 196 - - Antitoxin
LM505_RS14690 2982926..2986791 - 3866 Protein_2878 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-45)


Sequences

Toxin        


Download         Length: 55 a.a.        Molecular weight: 6080.21 Da        Isoelectric Point: 8.5145

>T223843 WP_080113450.1 NZ_CP086558:2982373-2982537 [Enterococcus faecalis]
ISLKNTNKTIVYCTTYETIQTILGFGMFTIALIALIVKLLKEDNRNDRCLTLAS

Download         Length: 165 bp

>T223843 NZ_CP119341:c2260560-2260456 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 196 bp

>AT223843 NZ_CP086558:c2982641-2982446 [Enterococcus faecalis]
TGTGCTGCAATAGAAACGAAAAGAGAGGTATGCTTCCAACATAGCTCTCTAATGTAGAACCGTTACTAACGGTGACAAAA
TTTTAAAGATTTTGAAATGACCGTCTAACTAGCCAAAGTTAAACAGCGGTCATTTCTGTTGTCTTCTTTAAGCAATTTCA
CAATCAGTGCAATCAAAGCAATGGTAAACATACCAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References