Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 2982373..2982641 | Replicon | chromosome |
Accession | NZ_CP086558 | ||
Organism | Enterococcus faecalis strain E512 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | - |
Locus tag | LM505_RS14685 | Protein ID | WP_080113450.1 |
Coordinates | 2982373..2982537 (+) | Length | 55 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 2982446..2982641 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LM505_RS14660 | 2977828..2978460 | - | 633 | WP_002358972.1 | RloB family protein | - |
LM505_RS14665 | 2978469..2979569 | - | 1101 | WP_229022098.1 | ATP-binding protein | - |
LM505_RS14670 | 2979569..2979763 | - | 195 | WP_229022099.1 | hypothetical protein | - |
LM505_RS14675 | 2980225..2981841 | + | 1617 | WP_010820356.1 | phosphatase PAP2/LCP family protein | - |
LM505_RS14680 | 2982149..2982253 | + | 105 | WP_023894767.1 | putative holin-like toxin | - |
LM505_RS14685 | 2982373..2982537 | + | 165 | WP_080113450.1 | putative holin-like toxin | Toxin |
- | 2982446..2982641 | - | 196 | - | - | Antitoxin |
LM505_RS14690 | 2982926..2986791 | - | 3866 | Protein_2878 | WxL domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 55 a.a. Molecular weight: 6080.21 Da Isoelectric Point: 8.5145
>T223843 WP_080113450.1 NZ_CP086558:2982373-2982537 [Enterococcus faecalis]
ISLKNTNKTIVYCTTYETIQTILGFGMFTIALIALIVKLLKEDNRNDRCLTLAS
ISLKNTNKTIVYCTTYETIQTILGFGMFTIALIALIVKLLKEDNRNDRCLTLAS
Download Length: 165 bp
>T223843 NZ_CP119341:c2260560-2260456 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA
Antitoxin
Download Length: 196 bp
>AT223843 NZ_CP086558:c2982641-2982446 [Enterococcus faecalis]
TGTGCTGCAATAGAAACGAAAAGAGAGGTATGCTTCCAACATAGCTCTCTAATGTAGAACCGTTACTAACGGTGACAAAA
TTTTAAAGATTTTGAAATGACCGTCTAACTAGCCAAAGTTAAACAGCGGTCATTTCTGTTGTCTTCTTTAAGCAATTTCA
CAATCAGTGCAATCAAAGCAATGGTAAACATACCAA
TGTGCTGCAATAGAAACGAAAAGAGAGGTATGCTTCCAACATAGCTCTCTAATGTAGAACCGTTACTAACGGTGACAAAA
TTTTAAAGATTTTGAAATGACCGTCTAACTAGCCAAAGTTAAACAGCGGTCATTTCTGTTGTCTTCTTTAAGCAATTTCA
CAATCAGTGCAATCAAAGCAATGGTAAACATACCAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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