Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 2827706..2827931 | Replicon | chromosome |
Accession | NZ_CP086558 | ||
Organism | Enterococcus faecalis strain E512 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | - |
Locus tag | LM505_RS13955 | Protein ID | WP_075551663.1 |
Coordinates | 2827830..2827931 (-) | Length | 34 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 2827706..2827885 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LM505_RS13925 | 2822922..2823875 | - | 954 | WP_010820307.1 | siderophore ABC transporter substrate-binding protein | - |
LM505_RS13930 | 2823914..2824669 | - | 756 | WP_002354962.1 | ATP-binding cassette domain-containing protein | - |
LM505_RS13935 | 2824666..2825631 | - | 966 | WP_002367415.1 | iron chelate uptake ABC transporter family permease subunit | - |
LM505_RS13940 | 2825628..2826575 | - | 948 | WP_002354960.1 | iron chelate uptake ABC transporter family permease subunit | - |
LM505_RS13945 | 2826760..2827212 | + | 453 | WP_002354958.1 | YueI family protein | - |
LM505_RS13950 | 2827397..2827498 | - | 102 | WP_075551663.1 | putative holin-like toxin | - |
- | 2827706..2827885 | + | 180 | - | - | Antitoxin |
LM505_RS13955 | 2827830..2827931 | - | 102 | WP_075551663.1 | putative holin-like toxin | Toxin |
LM505_RS13960 | 2828121..2830391 | - | 2271 | WP_002370088.1 | bifunctional glutamate--cysteine ligase/glutathione synthetase | - |
LM505_RS13965 | 2830562..2831068 | + | 507 | WP_010820308.1 | cysteine hydrolase family protein | - |
LM505_RS13970 | 2831258..2832154 | + | 897 | WP_002354953.1 | YitT family protein | - |
LM505_RS13975 | 2832205..2832603 | - | 399 | WP_002354951.1 | glyoxalase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 34 a.a. Molecular weight: 3599.34 Da Isoelectric Point: 4.5869
>T223832 WP_075551663.1 NZ_CP086558:c2827931-2827830 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNDKK
MSIEAALELMISFAAFVALLIFGILEATKNDKK
Download Length: 102 bp
>T223832 NZ_CP119340:c2174974-2174765 [Staphylococcus aureus]
ATGATACATCAAAATACGATTTACACAGCGGGAATTGAAACAGAAGAACAAGTAAGTCAATTGACAGAACGCATTTCAAA
TATGATAGGTGTTCATCAAGTGAATATTAATATAATAGATGGTCAAGTAACTGTATCGTATGAGACACCAGCAAATTTGA
ATAGTATTGAAAAAGAAATCTATGATGAAGGATACAAAATTGTAATTTAG
ATGATACATCAAAATACGATTTACACAGCGGGAATTGAAACAGAAGAACAAGTAAGTCAATTGACAGAACGCATTTCAAA
TATGATAGGTGTTCATCAAGTGAATATTAATATAATAGATGGTCAAGTAACTGTATCGTATGAGACACCAGCAAATTTGA
ATAGTATTGAAAAAGAAATCTATGATGAAGGATACAAAATTGTAATTTAG
Antitoxin
Download Length: 180 bp
>AT223832 NZ_CP086558:2827706-2827885 [Enterococcus faecalis]
TGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGT
TTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACC
GAAAATCAGTAGTGCAACAA
TGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGT
TTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACC
GAAAATCAGTAGTGCAACAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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