Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 501716..501944 | Replicon | chromosome |
Accession | NZ_CP086558 | ||
Organism | Enterococcus faecalis strain E512 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | - |
Locus tag | LM505_RS02530 | Protein ID | WP_219843903.1 |
Coordinates | 501716..501826 (+) | Length | 37 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 501809..501944 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LM505_RS02520 | 497148..499406 | + | 2259 | WP_229022106.1 | DNA helicase PcrA | - |
LM505_RS02525 | 499532..501562 | + | 2031 | WP_081115754.1 | NAD-dependent DNA ligase LigA | - |
LM505_RS02530 | 501716..501826 | + | 111 | WP_219843903.1 | putative holin-like toxin | Toxin |
- | 501809..501944 | - | 136 | - | - | Antitoxin |
LM505_RS02535 | 502144..502449 | + | 306 | WP_010819759.1 | Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC | - |
LM505_RS02540 | 502449..503918 | + | 1470 | WP_010819760.1 | Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA | - |
LM505_RS02545 | 503918..505348 | + | 1431 | WP_002358703.1 | Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB | - |
LM505_RS02550 | 505367..506455 | + | 1089 | WP_002355572.1 | diacylglycerol kinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 37 a.a. Molecular weight: 3805.59 Da Isoelectric Point: 5.9482
>T223821 WP_219843903.1 NZ_CP086558:501716-501826 [Enterococcus faecalis]
MSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS
MSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS
Download Length: 111 bp
>T223821 NZ_CP119334:1911282-1911560 [Vibrio alginolyticus]
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGACTTCAACCCTGATGCGGC
AGAAAAAACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAACAACCTTTGATGGGTGTACAACGAGATGGCA
TCCGCGGACGATTGCTCATTATTCCTGAGATTTCGATGATTGTCTCTTACTGGGTCGAGGGCGATATCATCAGAGTTATG
CGTGTACTCCACCAGAAACAAAAATTCCCTACGGATTGA
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGACTTCAACCCTGATGCGGC
AGAAAAAACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAACAACCTTTGATGGGTGTACAACGAGATGGCA
TCCGCGGACGATTGCTCATTATTCCTGAGATTTCGATGATTGTCTCTTACTGGGTCGAGGGCGATATCATCAGAGTTATG
CGTGTACTCCACCAGAAACAAAAATTCCCTACGGATTGA
Antitoxin
Download Length: 136 bp
>AT223821 NZ_CP086558:c501944-501809 [Enterococcus faecalis]
TGAAAAGAGAGATATGCAGGAACATACCTCTCTAATAGCCACTACCAGTTATAAGAACTGGTGGCTTACTGAGTTATTGG
TTTTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTT
TGAAAAGAGAGATATGCAGGAACATACCTCTCTAATAGCCACTACCAGTTATAAGAACTGGTGGCTTACTGAGTTATTGG
TTTTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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