Detailed information of TA system TA223816

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 348703..348897
• Replicon: chromosome
• Accession: NZ_CP086558
• Organism: Enterococcus faecalis strain E512

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: LM505_RS01805
• Protein ID: WP_015543884.1
• Coordinates: 348802..348897 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	348703..348767 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LM505_RS01790	344328..346076	+	1749	WP_010819726.1	PTS transporter subunit EIIC	-
LM505_RS01795	346067..348100	+	2034	WP_010819727.1	BglG family transcription antiterminator	-
LM505_RS01800	348111..348545	+	435	WP_010711967.1	PTS sugar transporter subunit IIA	-
-	348703..348767	+	65	-	-	Antitoxin
LM505_RS01805	348802..348897	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
LM505_RS01810	349143..350915	+	1773	WP_010819728.1	PTS mannitol-specific transporter subunit IIBC	-
LM505_RS01815	350930..351367	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
LM505_RS01820	351382..352536	+	1155	WP_010819729.1	mannitol-1-phosphate 5-dehydrogenase	-
LM505_RS01825	352604..353719	-	1116	WP_081115739.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T223816 WP_015543884.1 NZ_CP086558:c348897-348802 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T223816 NZ_CP119332:5436540-5436908 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCAGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACTCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCGGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCGGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGCTTGCGCGGATGA

Antitoxin

Nucleotide

• Length: 65 bp

>AT223816 NZ_CP086558:348703-348767 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGCAGTAGGGTGTCTTTTTTT

Structures

Antitoxin