Detailed information of TA system TA223216

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 349711..349905
• Replicon: chromosome
• Accession: NZ_CP086411
• Organism: Enterococcus faecalis strain R5

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: LMJ46_RS01835
• Protein ID: WP_015543884.1
• Coordinates: 349810..349905 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	349711..349775 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LMJ46_RS01820 (345323)	345323..347071	+	1749	WP_002389631.1	PTS transporter subunit EIIC	-
LMJ46_RS01825 (347062)	347062..349095	+	2034	WP_002361171.1	PRD domain-containing protein	-
LMJ46_RS01830 (349106)	349106..349540	+	435	WP_002358391.1	PTS sugar transporter subunit IIA	-
- (349711)	349711..349775	+	65	NuclAT_14	-	Antitoxin
LMJ46_RS01835 (349810)	349810..349905	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
LMJ46_RS01840 (350152)	350152..351924	+	1773	WP_002389635.1	PTS mannitol-specific transporter subunit IIBC	-
LMJ46_RS01845 (351939)	351939..352376	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
LMJ46_RS01850 (352391)	352391..353545	+	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
LMJ46_RS01855 (353612)	353612..354727	-	1116	WP_002389684.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T223216 WP_015543884.1 NZ_CP086411:c349905-349810 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T223216 NZ_CP118586:2554072-2554362 [Vibrio harveyi]
ATGATCTATAAACTCGACTTTAAAAAGAGCGCACTCAAAGAGTGGAAAAAGCTTGGCTCTACTCTGCAACAACAATTTAA
GAAAAAGCTAATCGAGCGCTTAGATAACCCACATGTTCCGGCTTCAAAACTTTCTGGAGCTGACAACATGTATAAAATTA
AGTTGCGTCAATCGGGCTACCGTCTCGTCTACAAAGTTGAAGACGATGTCATCATTGTAACCGTCTTAGCCGTCGGAAAA
CGCGAACGTAGCGATGTTTACCGTAAAGCCATGAAAAGGTTAGATGATTGA

Antitoxin

Nucleotide

• Length: 65 bp

>AT223216 NZ_CP086411:349711-349775 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Structures

Antitoxin