223128

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 4252739..4253281 Replicon chromosome
Accession NZ_CP086369
Organism Pectobacterium versatile strain A73-S18-O15

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag LLE50_RS19170 Protein ID WP_103972206.1
Coordinates 4253003..4253281 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag LLE50_RS19165 Protein ID WP_102116587.1
Coordinates 4252739..4252999 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LLE50_RS19135 (LLE50_19125) 4247794..4248004 + 211 Protein_3729 IS3 family transposase -
LLE50_RS19140 (LLE50_19130) 4248511..4249275 + 765 WP_226310566.1 glycosyltransferase family 2 protein -
LLE50_RS19145 (LLE50_19135) 4249287..4250246 + 960 WP_130622142.1 NAD-dependent epimerase/dehydratase family protein -
LLE50_RS19150 (LLE50_19140) 4250307..4251152 - 846 WP_130622141.1 dTDP-4-dehydrorhamnose reductase -
LLE50_RS19155 (LLE50_19145) 4251149..4251685 - 537 WP_130622140.1 dTDP-4-dehydrorhamnose 3,5-epimerase -
LLE50_RS19160 (LLE50_19150) 4251687..4252556 - 870 WP_130622181.1 glucose-1-phosphate thymidylyltransferase RfbA -
LLE50_RS19165 (LLE50_19155) 4252739..4252999 + 261 WP_102116587.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LLE50_RS19170 (LLE50_19160) 4253003..4253281 + 279 WP_103972206.1 type II toxin-antitoxin system YafQ family toxin Toxin
LLE50_RS19175 (LLE50_19165) 4253514..4254410 + 897 WP_103860289.1 sugar phosphate nucleotidyltransferase -
LLE50_RS19180 (LLE50_19170) 4254641..4256047 + 1407 WP_039492568.1 NADP-dependent phosphogluconate dehydrogenase -
LLE50_RS19185 (LLE50_19175) 4256515..4256808 + 294 WP_010296810.1 hypothetical protein -
LLE50_RS19190 (LLE50_19180) 4256884..4257561 + 678 WP_165791259.1 YjbF family lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - wza / wzb / ugd / wbtL 4227803..4253281 25478


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-85)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 11156.81 Da        Isoelectric Point: 10.0684

>T223128 WP_103972206.1 NZ_CP086369:4253003-4253281 [Pectobacterium versatile]
MKKQREIAYSGQFQRDVKKAQRRHKNMNKLKTLMQLLLEDKRPLPQEYQDHPLQGNYKGYRDAHIEPDWLLIYKLTDDVL
RFERTGTHADLF

Download         Length: 279 bp

>T223128 NZ_CP118536:c4232294-4231803 [Salmonella enterica subsp. enterica serovar Typhi]
ATGATCTCCACCCCTGAGCCGCTTCATGCCGGACATATTCTTACTCCGTTTTGCTGCGGTGTGGATTCTATAGATAACTG
GCTGAAACAGCGGGCGATGAAAAATCAGACCACTGGCGCGTCCCGTACCTTTGTGTGTTGTGGCAGCGATTCGAACGTAC
TGGCCTATTACTCGCTGGCGTCCAGCGCGGTCACGACGAATACCTCCCCCGGTCGCTTTCGTCGCAATATGCCTGACCCG
ATTCCGGTTGTGGTATTGGGGCGTCTGGCGGTGGATAAATCGCTTCATGGGCAGGGCGTCGCTCGGGCGCTGGTACGCGA
CGCAGGGCTGCGGGTTATTCAGGTGGCGGAGACTATCGGCATTCGTGGGATGCTGGTTCACGCCCTGTCGGATGAAGCGC
GGGAATTTTATCAGTGGGTGGGGTTTGTACCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTGTTTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9308.75 Da        Isoelectric Point: 5.0628

>AT223128 WP_102116587.1 NZ_CP086369:4252739-4252999 [Pectobacterium versatile]
MAANAFVRARIDENLKNEAAEVLASMGLTVSDLVRITLTKVAKEKALPFDMHVPNKLTAQTMADSEKGVDVYTAKDAADL
FDKLGI

Download         Length: 261 bp

>AT223128 NZ_CP118536:c4232584-4232291 [Salmonella enterica subsp. enterica serovar Typhi]
ATGCCAGCCGCAAACAGTATGGCGATGAAACGTGAAACTCTGAACCTGCGTATCAAACCCGCCGAGCGCGATCTTATTGA
TCGAGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGTTGGAAGCTGCCCGTGCTGCCGCAGAAGAAGTGCTTA
TCGAACAACGCATCATTATGGCCGATCCAGAGGCTTATCAGGAATTTCTCGTTCGTTTGGATCAAACACCTTCACCTAAT
GCCGCACTGCGTAAAACCATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References