223112

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 2431713..2433064 Replicon chromosome
Accession NZ_CP086369
Organism Pectobacterium versatile strain A73-S18-O15

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag LLE50_RS11005 Protein ID WP_125232112.1
Coordinates 2432024..2433064 (+) Length 347 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag LLE50_RS11000 Protein ID WP_130621236.1
Coordinates 2431713..2432027 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LLE50_RS10975 (LLE50_10970) 2427538..2428572 + 1035 WP_103862830.1 putative FMN-dependent luciferase-like monooxygenase -
LLE50_RS10980 (LLE50_10975) 2428569..2429702 + 1134 WP_130621234.1 alkylhydroperoxidase domain protein -
LLE50_RS10985 (LLE50_10980) 2429759..2430268 - 510 WP_039542420.1 phenolic acid decarboxylase -
LLE50_RS10990 (LLE50_10985) 2430371..2431243 + 873 WP_103862832.1 LysR family transcriptional regulator -
LLE50_RS10995 (LLE50_10990) 2431402..2431728 + 327 WP_130621235.1 helix-turn-helix domain-containing protein -
LLE50_RS11000 (LLE50_10995) 2431713..2432027 + 315 WP_130621236.1 HipA N-terminal domain-containing protein Antitoxin
LLE50_RS11005 (LLE50_11000) 2432024..2433064 + 1041 WP_125232112.1 HipA domain-containing protein Toxin
LLE50_RS11010 (LLE50_11005) 2433125..2433748 - 624 WP_039474438.1 LysE family translocator -
LLE50_RS11015 (LLE50_11010) 2434026..2434781 + 756 WP_130621237.1 thiol:disulfide interchange protein DsbG -
LLE50_RS11020 (LLE50_11015) 2434815..2435720 - 906 WP_130621238.1 siderophore-interacting protein -
LLE50_RS11025 (LLE50_11020) 2435975..2436226 + 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
LLE50_RS11030 (LLE50_11025) 2436223..2436510 + 288 WP_015842269.1 type II toxin-antitoxin system RelE/ParE family toxin -
LLE50_RS11035 (LLE50_11030) 2436702..2437661 - 960 WP_103943153.1 bacteriophage abortive infection AbiH family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(57-307)

Antitoxin

HipA, N-terminal subdomain 1

(5-98)


Sequences

Toxin        


Download         Length: 347 a.a.        Molecular weight: 39562.56 Da        Isoelectric Point: 6.3862

>T223112 WP_125232112.1 NZ_CP086369:2432024-2433064 [Pectobacterium versatile]
MTTCRILLTPLTHEEEMATGYSRKGLKHLAGSIHASPDLRFTRQQFMHDLPQTQKGMSISGYQPKIQMVLQDRAFIVVDH
QGLYILKPSPIEFPHLAENEHATMTLMARLGFAVPPHGLLRFKPDQADDEPEFAFVIKRFDRDEKTGHPIHQEQLDGAMG
IGEKFGKIRADGRQYISYERLALFLSEHVNDNIVFKIDLFRRIAYAYMLGNNDMHLRNFGLIHSRSGQLMLAPIYDFVSV
APYPTYFSSCFMALPLLIQEEGDEALAPGFETAYGEYLGMDFILFGQRIGLSEKLTKKLLADFIKEAECVESTYRDSFMP
AEAIDTTLRCYRHRLNLMSILDAERI

Download         Length: 1041 bp

>T223112 NZ_CP118530:c1377188-1376910 [Vibrio harveyi]
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGACTTTAACCCTGATGCGGC
AGAAAAAACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAACAACCTTTAATGGGTGTACAACGCGATGGCA
TCCGCGGACGATTGCTCATTATTCCTGAGATTTCGATGATTGTGTCTTACTGGCTCGAGGGCGATATCATCCGAGTTATG
CGTGTACTCCACCAGAAACAAAAATTCCCTACAGATTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11840.54 Da        Isoelectric Point: 7.1966

>AT223112 WP_130621236.1 NZ_CP086369:2431713-2432027 [Pectobacterium versatile]
VRRQVKVYLYGVHIGQLSQDDEGYLFEYKKSYIGPPLSLSLPLQTGTFRSKTLPPYFASLAPEGWLRRQYSQLQHLDEKD
LFGILIQNGKNLIGAVQLIAEDEA

Download         Length: 315 bp

>AT223112 NZ_CP118530:c1377469-1377185 [Vibrio harveyi]
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAAATGGCTGAGAGCCAAGGTCGAAC
TTTAAGTGATGCTTGCCGTGAACTTACTGAGCAACTCGCTGAACAACAAAGAAAAACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCCGTTTTCGTTGAGCACCAAACTGCTAAATCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References