Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 2943530..2944072 Replicon chromosome
Accession NZ_CP086253
Organism Pectobacterium aquaticum strain A212-S19-A16

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag DMB82_RS13705 Protein ID WP_103972206.1
Coordinates 2943530..2943808 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag DMB82_RS13710 Protein ID WP_102116587.1
Coordinates 2943812..2944072 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DMB82_RS13685 (DMB82_0013730) 2939278..2939955 - 678 WP_116162195.1 YjbF family lipoprotein -
DMB82_RS13690 (DMB82_0013735) 2940031..2940333 - 303 WP_116162193.1 hypothetical protein -
DMB82_RS13695 (DMB82_0013740) 2940765..2942171 - 1407 WP_116162191.1 NADP-dependent phosphogluconate dehydrogenase -
DMB82_RS13700 (DMB82_0013745) 2942402..2943298 - 897 WP_102116586.1 sugar phosphate nucleotidyltransferase -
DMB82_RS13705 (DMB82_0013750) 2943530..2943808 - 279 WP_103972206.1 type II toxin-antitoxin system YafQ family toxin Toxin
DMB82_RS13710 (DMB82_0013755) 2943812..2944072 - 261 WP_102116587.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
DMB82_RS13715 (DMB82_0013760) 2944255..2945124 + 870 WP_116155746.1 glucose-1-phosphate thymidylyltransferase RfbA -
DMB82_RS13720 (DMB82_0013765) 2945126..2945662 + 537 WP_116162189.1 dTDP-4-dehydrorhamnose 3,5-epimerase -
DMB82_RS13725 (DMB82_0013770) 2945659..2946510 + 852 WP_116162187.1 dTDP-4-dehydrorhamnose reductase -
DMB82_RS13730 (DMB82_0013775) 2946735..2947051 + 317 Protein_2682 IS1-like element transposase -
DMB82_RS13740 (DMB82_0013785) 2948652..2948975 + 324 Protein_2684 IS1 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-85)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 11156.81 Da        Isoelectric Point: 10.0684

>T222833 WP_103972206.1 NZ_CP086253:c2943808-2943530 [Pectobacterium aquaticum]
MKKQREIAYSGQFQRDVKKAQRRHKNMNKLKTLMQLLLEDKRPLPQEYQDHPLQGNYKGYRDAHIEPDWLLIYKLTDDVL
RFERTGTHADLF

Download         Length: 279 bp

>T222833 NZ_CP118144:c1778141-1777959 [Pseudomonas chlororaphis]
GTGGACAGTCGGTATTTGATCGGCCAAATCGTCGCAGACGGTTGGTATCTGGTCAGGGTCAGGGGCAGTCACCACCATTT
CAAGCATCCCCATAAACCGGGGCTGGTGACCGTTCCCCATCCCAAAAAGGACCTGCTGAGAAAAACCGCCATCAGTATTC
TGAAACAGGCGCTGCTCATGTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9308.75 Da        Isoelectric Point: 5.0628

>AT222833 WP_102116587.1 NZ_CP086253:c2944072-2943812 [Pectobacterium aquaticum]
MAANAFVRARIDENLKNEAAEVLASMGLTVSDLVRITLTKVAKEKALPFDMHVPNKLTAQTMADSEKGVDVYTAKDAADL
FDKLGI

Download         Length: 261 bp

>AT222833 NZ_CP118144:c1777926-1777519 [Pseudomonas chlororaphis]
ATGCTTTACCCGATTGCAATTTCAATGGGCGATGACGAACACGCCTGGGGGGTGGAAGTCCCCGATATTCCTGGCTGTTT
CTCGGCCGGCGACGACCTCGACGACGCCATGGCCATGGCCCGCGAAGCCATCGAAGGGCACTTCGAGATTCTCGCTGAAG
ACGGTGCCCCCATCCCGCACGCCAACAAGGTCACCCTGCACGCGGCCAACCCCCGGTACGCAGGCTGCACCTGGGCGCTG
ATCGACATCGATGTCACCAAGTACCTGGGCAAGGCGCAGAAGCTCAACATCACCCTGCCCGGCTACTTGCTGAACCGCAT
CGACGAATACGTGCTGCATCACCCGGAAGCCAAGAGCCGCTCGGGTTTTCTCGCTTCGGCTGCACTGAAGGTATTGCAGC
AAGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References