Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 601198..601700 Replicon chromosome
Accession NZ_CP086253
Organism Pectobacterium aquaticum strain A212-S19-A16

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag DMB82_RS02815 Protein ID WP_116156382.1
Coordinates 601446..601700 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag DMB82_RS02810 Protein ID WP_102117218.1
Coordinates 601198..601449 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DMB82_RS02795 (DMB82_0002805) 597598..598557 + 960 WP_116164015.1 ABC transporter permease -
DMB82_RS02800 (DMB82_0002810) 598550..599416 + 867 WP_102117216.1 ABC transporter permease -
DMB82_RS02805 (DMB82_0002815) 599413..601122 + 1710 WP_102117217.1 ABC transporter ATP-binding protein -
DMB82_RS02810 (DMB82_0002820) 601198..601449 + 252 WP_102117218.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
DMB82_RS02815 (DMB82_0002825) 601446..601700 + 255 WP_116156382.1 Txe/YoeB family addiction module toxin Toxin
DMB82_RS02820 (DMB82_0002830) 602078..603049 + 972 WP_116156383.1 reverse transcriptase domain-containing protein -
DMB82_RS02825 (DMB82_0002835) 603046..604374 + 1329 WP_116156384.1 AAA family ATPase -
DMB82_RS02830 (DMB82_0002840) 604562..605416 - 855 WP_102117219.1 helix-turn-helix domain-containing protein -
DMB82_RS02835 (DMB82_0002845) 605441..606280 - 840 WP_116164013.1 HTH-type transcriptional activator RhaS -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10243.82 Da        Isoelectric Point: 8.0353

>T222828 WP_116156382.1 NZ_CP086253:601446-601700 [Pectobacterium aquaticum]
VKLIWSEEAWEDYLYWQDIDKRMVKKINELIKETRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLIYAITDDAMMIAAC
RYHY

Download         Length: 255 bp

>T222828 NZ_CP118144:439991-440272 [Pseudomonas chlororaphis]
ATGACTTATAAGCTCCAGTTTCTGCCTTCGGCACGTAAGGAATGGGACAAGCTCGGTCATACCCTGCGCGAGCAATTCAA
GAAGAAGCTGGCCGAGCGCCTGGAAATGCCACGGGTGTCCGCGGATGCCCTTCACGGCATGGCGGACTGCTACAAGATCA
AGCTCAAGGCCTCTGACTATCGCCTGGTTTACCAAGTGATCGAGGATCAGGTGGTGGTTTCGGTGGTGGCCGTGGGCAAA
CGTGAACGCAGCGCCGTGTATGAGCGGGCACGAAAGCGCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9390.68 Da        Isoelectric Point: 4.8223

>AT222828 WP_102117218.1 NZ_CP086253:601198-601449 [Pectobacterium aquaticum]
MRTISYSEARQHLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNSIESLKAGNGEERD
IIE

Download         Length: 252 bp

>AT222828 NZ_CP118144:439756-440001 [Pseudomonas chlororaphis]
ATGCAAAGCGTATTGGCTGATAAAGCTGTCAGCGTGTCTGAACTGAAAAAAAACCCCTCGGCTGTCCTGAGCGGCGCACA
CGGTGGTCCGGTTGCGGTGCTCAATCACAACCGGGTCATGGGCTATATGGTCCCGGCCGACGTGTTTGAAGCCATGATGG
AGCGTCTTGACGATCTTGAACTGGCGGAGATTGTCCGTGCCCGTCGGCACGAGACCCCAGTCCCGGTAAATCTGGATGAC
TTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References