Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 160565..161418 Replicon chromosome
Accession NZ_CP086253
Organism Pectobacterium aquaticum strain A212-S19-A16

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag DMB82_RS00705 Protein ID WP_116164089.1
Coordinates 160930..161418 (+) Length 163 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag DMB82_RS00700 Protein ID WP_116164087.1
Coordinates 160565..160906 (+) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DMB82_RS00670 (DMB82_0000670) 156303..156617 - 315 WP_102118154.1 BrnA antitoxin family protein -
DMB82_RS00675 (DMB82_0000675) 156604..156834 - 231 WP_072037288.1 BrnT family toxin -
DMB82_RS00680 (DMB82_0000680) 157071..157838 - 768 WP_116155942.1 triose-phosphate isomerase -
DMB82_RS00685 (DMB82_0000685) 158004..158603 - 600 WP_102118156.1 YiiQ family protein -
DMB82_RS00690 (DMB82_0000690) 158881..159303 + 423 WP_102118157.1 DUF805 domain-containing protein -
DMB82_RS00695 (DMB82_0000695) 159321..160067 - 747 WP_010281538.1 ferredoxin--NADP(+) reductase -
DMB82_RS00700 (DMB82_0000700) 160565..160906 + 342 WP_116164087.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
DMB82_RS00705 (DMB82_0000705) 160930..161418 + 489 WP_116164089.1 type II toxin-antitoxin system YhaV family toxin Toxin
DMB82_RS00710 (DMB82_0000710) 161731..161921 + 191 Protein_141 IS4/IS5 family transposase -
DMB82_RS00715 (DMB82_0000715) 161976..162749 - 774 WP_116164091.1 hypothetical protein -
DMB82_RS00720 (DMB82_0000725) 163074..164084 - 1011 WP_116164095.1 class II fructose-bisphosphatase -
DMB82_RS00725 (DMB82_0000730) 164339..165850 - 1512 WP_102118159.1 glycerol kinase GlpK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(11-148)

Antitoxin

SpoVT-AbrB domain

(18-53)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 18532.26 Da        Isoelectric Point: 7.3202

>T222824 WP_116164089.1 NZ_CP086253:160930-161418 [Pectobacterium aquaticum]
MEYLEVNGWKVFFHSCFLLQIAELTQKVVELKAAKPGEYLGKKETKLLHAIERVIEEWIAADPLNAQYRQGDTLGDEFKH
WFRAKFLSQFRLFYRCSAEHKTIIIGWVNDFETLRAYGSKTDAYKVFSGMLKAGDPPDDWEKLLSEAKAATATSSISGFL
GK

Download         Length: 489 bp

>T222824 NZ_CP118143:c2599210-2598920 [Pseudomonas chlororaphis]
ATGTCCGACACCCTGCTTCCCTTCGACATCGCCGCCCTGCTCGACAGCGACCAGGCGATCAGCGAATACCTGTCCCAGGT
CCTGGCCGATGGCGATACCGATGAACTGATCCGCGCCCTGGGCCATGTCGCCAGGGCCCGGGGCATGACGCAGATTGCCA
AGGCCACCGGCCAGGGCCGGGCCAGCCTCTACAAGGCTTTTGCCCCGGGTGCCAAGCCGCGTTTCGATACCGTGGTCAAG
GTCATGCGCGCGCTGGGCCTGCAGCTGTGCACCACCGTGTCCCGCGGCTGA

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12654.41 Da        Isoelectric Point: 4.4335

>AT222824 WP_116164087.1 NZ_CP086253:160565-160906 [Pectobacterium aquaticum]
MTIHINTADVSLRAESRLTERSQTTIPAAIRDALHLKPGEYIKYTLLAGGKVIMSRQEEEQDDPVISQFLAFLENDMKKN
PQNIYPVPVVFWESIKALTAGVEVDLDAPLTDD

Download         Length: 342 bp

>AT222824 NZ_CP118143:c2599505-2599212 [Pseudomonas chlororaphis]
ATGGATTACGAGATCCTGCAGACGACCGTCTTTGCCCAATGGCACACCACGCTACGGGACCTGCGCGCCAGGATAGCCAT
CGCTCGGCGTATCGAGCGGGCTTCGGCGGGCAACCTGGGCGATGTGAAAAACCTCGGCGGCGGTCTCTCGGAAATGCGCG
TGAATATGGGAGCCGGCTACCGCATCTATTTCACCGTGCGCGGTAATACCCTCATCGTCCTGCTGCTGGGCGGCGACAAG
TCCACCCAGCCTGCCGATATCTGCCAGGCCCGTTCCCTGGCCAAGGAGTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References