Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-ohsC/Ldr(toxin)
Location 1011533..1011755 Replicon chromosome
Accession NZ_CP086220
Organism Escherichia coli strain 779

Toxin (Protein)


Gene name ldrD Uniprot ID B7LGX8
Locus tag LMB17_RS04935 Protein ID WP_000170965.1
Coordinates 1011533..1011640 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name ohsC
Locus tag -
Coordinates 1011688..1011755 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LMB17_RS04905 (1007388) 1007388..1008221 + 834 WP_000456467.1 peptide chain release factor N(5)-glutamine methyltransferase -
LMB17_RS04910 (1008218) 1008218..1008610 + 393 WP_000200378.1 invasion regulator SirB2 -
LMB17_RS04915 (1008614) 1008614..1009423 + 810 WP_001257044.1 invasion regulator SirB1 -
LMB17_RS04920 (1009459) 1009459..1010313 + 855 WP_000811065.1 3-deoxy-8-phosphooctulonate synthase -
LMB17_RS04925 (1010462) 1010462..1010569 - 108 WP_000170954.1 type I toxin-antitoxin system toxin Ldr family protein -
- (1010619) 1010619..1010682 + 64 NuclAT_40 - -
- (1010619) 1010619..1010682 + 64 NuclAT_40 - -
- (1010619) 1010619..1010682 + 64 NuclAT_40 - -
- (1010619) 1010619..1010682 + 64 NuclAT_40 - -
- (1010619) 1010619..1010682 + 64 NuclAT_42 - -
- (1010619) 1010619..1010682 + 64 NuclAT_42 - -
- (1010619) 1010619..1010682 + 64 NuclAT_42 - -
- (1010619) 1010619..1010682 + 64 NuclAT_42 - -
- (1010617) 1010617..1010683 + 67 NuclAT_27 - -
- (1010617) 1010617..1010683 + 67 NuclAT_27 - -
- (1010617) 1010617..1010683 + 67 NuclAT_27 - -
- (1010617) 1010617..1010683 + 67 NuclAT_27 - -
- (1010617) 1010617..1010683 + 67 NuclAT_29 - -
- (1010617) 1010617..1010683 + 67 NuclAT_29 - -
- (1010617) 1010617..1010683 + 67 NuclAT_29 - -
- (1010617) 1010617..1010683 + 67 NuclAT_29 - -
- (1010617) 1010617..1010683 + 67 NuclAT_31 - -
- (1010617) 1010617..1010683 + 67 NuclAT_31 - -
- (1010617) 1010617..1010683 + 67 NuclAT_31 - -
- (1010617) 1010617..1010683 + 67 NuclAT_31 - -
- (1010617) 1010617..1010683 + 67 NuclAT_33 - -
- (1010617) 1010617..1010683 + 67 NuclAT_33 - -
- (1010617) 1010617..1010683 + 67 NuclAT_33 - -
- (1010617) 1010617..1010683 + 67 NuclAT_33 - -
- (1010617) 1010617..1010683 + 67 NuclAT_35 - -
- (1010617) 1010617..1010683 + 67 NuclAT_35 - -
- (1010617) 1010617..1010683 + 67 NuclAT_35 - -
- (1010617) 1010617..1010683 + 67 NuclAT_35 - -
- (1010617) 1010617..1010683 + 67 NuclAT_37 - -
- (1010617) 1010617..1010683 + 67 NuclAT_37 - -
- (1010617) 1010617..1010683 + 67 NuclAT_37 - -
- (1010617) 1010617..1010683 + 67 NuclAT_37 - -
LMB17_RS04930 (1010997) 1010997..1011104 - 108 WP_000170926.1 type I toxin-antitoxin system toxin Ldr family protein -
- (1011157) 1011157..1011218 + 62 NuclAT_39 - -
- (1011157) 1011157..1011218 + 62 NuclAT_39 - -
- (1011157) 1011157..1011218 + 62 NuclAT_39 - -
- (1011157) 1011157..1011218 + 62 NuclAT_39 - -
- (1011157) 1011157..1011218 + 62 NuclAT_41 - -
- (1011157) 1011157..1011218 + 62 NuclAT_41 - -
- (1011157) 1011157..1011218 + 62 NuclAT_41 - -
- (1011157) 1011157..1011218 + 62 NuclAT_41 - -
- (1011157) 1011157..1011219 + 63 NuclAT_28 - -
- (1011157) 1011157..1011219 + 63 NuclAT_28 - -
- (1011157) 1011157..1011219 + 63 NuclAT_28 - -
- (1011157) 1011157..1011219 + 63 NuclAT_28 - -
- (1011157) 1011157..1011219 + 63 NuclAT_30 - -
- (1011157) 1011157..1011219 + 63 NuclAT_30 - -
- (1011157) 1011157..1011219 + 63 NuclAT_30 - -
- (1011157) 1011157..1011219 + 63 NuclAT_30 - -
- (1011157) 1011157..1011219 + 63 NuclAT_32 - -
- (1011157) 1011157..1011219 + 63 NuclAT_32 - -
- (1011157) 1011157..1011219 + 63 NuclAT_32 - -
- (1011157) 1011157..1011219 + 63 NuclAT_32 - -
- (1011157) 1011157..1011219 + 63 NuclAT_34 - -
- (1011157) 1011157..1011219 + 63 NuclAT_34 - -
- (1011157) 1011157..1011219 + 63 NuclAT_34 - -
- (1011157) 1011157..1011219 + 63 NuclAT_34 - -
- (1011157) 1011157..1011219 + 63 NuclAT_36 - -
- (1011157) 1011157..1011219 + 63 NuclAT_36 - -
- (1011157) 1011157..1011219 + 63 NuclAT_36 - -
- (1011157) 1011157..1011219 + 63 NuclAT_36 - -
- (1011157) 1011157..1011219 + 63 NuclAT_38 - -
- (1011157) 1011157..1011219 + 63 NuclAT_38 - -
- (1011157) 1011157..1011219 + 63 NuclAT_38 - -
- (1011157) 1011157..1011219 + 63 NuclAT_38 - -
- (1011157) 1011157..1011220 + 64 NuclAT_16 - -
- (1011157) 1011157..1011220 + 64 NuclAT_16 - -
- (1011157) 1011157..1011220 + 64 NuclAT_16 - -
- (1011157) 1011157..1011220 + 64 NuclAT_16 - -
- (1011157) 1011157..1011220 + 64 NuclAT_18 - -
- (1011157) 1011157..1011220 + 64 NuclAT_18 - -
- (1011157) 1011157..1011220 + 64 NuclAT_18 - -
- (1011157) 1011157..1011220 + 64 NuclAT_18 - -
- (1011157) 1011157..1011220 + 64 NuclAT_20 - -
- (1011157) 1011157..1011220 + 64 NuclAT_20 - -
- (1011157) 1011157..1011220 + 64 NuclAT_20 - -
- (1011157) 1011157..1011220 + 64 NuclAT_20 - -
- (1011157) 1011157..1011220 + 64 NuclAT_22 - -
- (1011157) 1011157..1011220 + 64 NuclAT_22 - -
- (1011157) 1011157..1011220 + 64 NuclAT_22 - -
- (1011157) 1011157..1011220 + 64 NuclAT_22 - -
- (1011157) 1011157..1011220 + 64 NuclAT_24 - -
- (1011157) 1011157..1011220 + 64 NuclAT_24 - -
- (1011157) 1011157..1011220 + 64 NuclAT_24 - -
- (1011157) 1011157..1011220 + 64 NuclAT_24 - -
- (1011157) 1011157..1011220 + 64 NuclAT_26 - -
- (1011157) 1011157..1011220 + 64 NuclAT_26 - -
- (1011157) 1011157..1011220 + 64 NuclAT_26 - -
- (1011157) 1011157..1011220 + 64 NuclAT_26 - -
LMB17_RS04935 (1011533) 1011533..1011640 - 108 WP_000170965.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- (1011688) 1011688..1011755 + 68 NuclAT_15 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_15 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_15 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_15 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_17 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_17 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_17 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_17 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_19 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_19 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_19 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_19 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_21 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_21 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_21 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_21 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_23 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_23 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_23 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_23 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_25 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_25 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_25 - Antitoxin
- (1011688) 1011688..1011755 + 68 NuclAT_25 - Antitoxin
LMB17_RS04940 (1012045) 1012045..1013145 - 1101 WP_001295620.1 sodium-potassium/proton antiporter ChaA -
LMB17_RS04945 (1013415) 1013415..1013645 + 231 WP_001146442.1 putative cation transport regulator ChaB -
LMB17_RS04950 (1013803) 1013803..1014498 + 696 WP_001355927.1 glutathione-specific gamma-glutamylcyclotransferase -
LMB17_RS04955 (1014542) 1014542..1014895 - 354 WP_001169669.1 DsrE/F sulfur relay family protein YchN -
LMB17_RS04960 (1015080) 1015080..1016474 + 1395 WP_000086213.1 inverse autotransporter invasin YchO -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4001.77 Da        Isoelectric Point: 11.4779

>T222783 WP_000170965.1 NZ_CP086220:c1011640-1011533 [Escherichia coli]
MTLAQFAMTFWHDLAAPILAGIITAAIVSWWRNRK

Download         Length: 108 bp

>T222783 NZ_CP118138:3200246-3200545 [Pseudomonas chlororaphis]
ATGATCGAGATCAAACAGACCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGGATTCCAGAGCCAGGGCGTTGATCGC
TGCGCGGATTTTTCGCCTGGCCAACGGCCTTGCCGGTGACGTGTCACCGGTGGGCGAGGGCGTCAGTGAGCTGCGCATCC
ATTACGGGCCGGGCTACCGGGTTTACTTCCAGCAGCTCGGTTCGCAACTTGTCATTCTGTTATGCGGCGGCGACAAGAGT
CGCCAGGGCCGCGATATCGAACTGGCCAAACAGCTGGCCCGTCGTTGGAGCCGATCATGA

Antitoxin


Download         Length: 68 bp

>AT222783 NZ_CP086220:1011688-1011755 [Escherichia coli]
GTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0Y029

Antitoxin

Download structure file

References