Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2713701..2713963 Replicon chromosome
Accession NZ_CP086215
Organism Staphylococcus aureus strain Patient 14 Isolate 02

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag LLZ98_RS13480 Protein ID WP_001802298.1
Coordinates 2713701..2713805 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2713800..2713963 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LLZ98_RS13465 2710498..2711280 + 783 WP_000908182.1 ABC transporter ATP-binding protein -
LLZ98_RS13470 2711348..2712205 + 858 WP_000370923.1 HAD family hydrolase -
LLZ98_RS13475 2712863..2713021 - 159 WP_001792784.1 hypothetical protein -
LLZ98_RS13480 2713701..2713805 + 105 WP_001802298.1 hypothetical protein Toxin
- 2713800..2713963 - 164 - - Antitoxin
LLZ98_RS13490 2714238..2715329 - 1092 WP_000495669.1 hypothetical protein -
LLZ98_RS13495 2715595..2716572 - 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
LLZ98_RS13500 2716574..2716894 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
LLZ98_RS13505 2717046..2717711 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T222773 WP_001802298.1 NZ_CP086215:2713701-2713805 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T222773 NZ_CP118137:542923-543105 [Pseudomonas chlororaphis]
ATGCGCAGTCGGGAACTGATCAGGATGATCGAGGAGGACGGGTGGTATCTGATCGCGGTCAAAGGCAGTCATCACCAGTA
CAAGCATCTGCACAAGCCGGGGCGGGTCACTATCCCTCACCCGGATGCGGATCTGCCCAGGGGCACGATCCACAGCATCT
TGAAACAGGCGGGCCTGAAATGA

Antitoxin


Download         Length: 164 bp

>AT222773 NZ_CP086215:c2713963-2713800 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References