Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
| Location | 2668174..2668763 | Replicon | chromosome |
| Accession | NZ_CP086200 | ||
| Organism | Xanthomonas oryzae pv. oryzae strain GXO2006 | ||
Toxin (Protein)
| Gene name | graT | Uniprot ID | G7TIR7 |
| Locus tag | LLC55_RS12665 | Protein ID | WP_012443754.1 |
| Coordinates | 2668482..2668763 (-) | Length | 94 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | LLC55_RS12660 | Protein ID | WP_011260746.1 |
| Coordinates | 2668174..2668464 (-) | Length | 97 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LLC55_RS12630 (LLC55_12635) | 2663327..2663935 | - | 609 | WP_011409746.1 | DUF4123 domain-containing protein | - |
| LLC55_RS12635 (LLC55_12640) | 2663938..2664360 | - | 423 | WP_042465811.1 | PAAR domain-containing protein | - |
| LLC55_RS12640 (LLC55_12645) | 2664488..2664814 | - | 327 | WP_228329596.1 | hypothetical protein | - |
| LLC55_RS12645 (LLC55_12650) | 2665069..2665401 | + | 333 | WP_011260743.1 | hypothetical protein | - |
| LLC55_RS12650 (LLC55_12655) | 2665561..2665748 | + | 188 | Protein_2427 | hypothetical protein | - |
| LLC55_RS12655 (LLC55_12660) | 2665851..2667245 | - | 1395 | WP_027703652.1 | type III secretion system effector XopQ | - |
| LLC55_RS12660 (LLC55_12665) | 2668174..2668464 | - | 291 | WP_011260746.1 | HigA family addiction module antitoxin | Antitoxin |
| LLC55_RS12665 (LLC55_12670) | 2668482..2668763 | - | 282 | WP_012443754.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LLC55_RS12670 (LLC55_12675) | 2668858..2671110 | - | 2253 | WP_069960050.1 | exodeoxyribonuclease V subunit alpha | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 11066.83 Da Isoelectric Point: 10.5318
>T222722 WP_012443754.1 NZ_CP086200:c2668763-2668482 [Xanthomonas oryzae pv. oryzae]
VIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQRRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH
VIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQRRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH
Download Length: 282 bp
>T222722 NZ_CP118054:c1366547-1365780 [Streptococcus anginosus]
ATGAGACTGGAAGAATTTAGTGAGGATGAATTTCAGAAAGCCTTACAGCGAACGATTCGAGCTCTAACTCGTGGAAAGAC
GATTCCAGAACAACCTCAAGCCATTTTGCTTGGTGGTCAAAGCGGAGCAGGAAAGACGACCATCCATCGAATTAAGCAAA
AAGAATTTCAAGGGAATATCATTATCATTGACGGTGATAGCTACCGTTCTCAGCACCCAAATTACTTAGCTCTGCAAGAA
AAGTATGGTAAGGATAGTGTGGATTATACAAAGGGATTTGCAGGAAAAATGGTAGAGTATCTGGTTGATGAACTCAGTAA
GCAAGGTTATCATTTGTTGATTGAAGGGACTTTGCGAACCACTCAAGTTCCACGGCAGACTGCTCAATTACTACGAAAAA
AAGGCTACCATATTTCTTTGGCTGTGATTGGCACCAAACCAGAACTTTCCTATCTCAGTACCTTGATTCGTTATGAGGAA
CTTTACACAATAAATCCTAATCAGGCCAGAGCAACCCCTAAAGAACATCATGATGGTATTGTAGAGCATTTGGTTGATAA
CCTAAGAGAGTTAGAAAACGATAAGCTCTTTGACCGCATTCAAATTTACCAAAGAGATAGGACTTGTATTTACGATTCTG
AAACGGATGAGATTTCCGCAGCAACAGTTCTTCAAGGATGCCTCTTCGGTAAATGGAGTAAGGTGGAGGAAGAGATGATG
AAGGCGGGAACAGGAACGGTTGAGAGATTTGTGTTGGAAGAACGGTAG
ATGAGACTGGAAGAATTTAGTGAGGATGAATTTCAGAAAGCCTTACAGCGAACGATTCGAGCTCTAACTCGTGGAAAGAC
GATTCCAGAACAACCTCAAGCCATTTTGCTTGGTGGTCAAAGCGGAGCAGGAAAGACGACCATCCATCGAATTAAGCAAA
AAGAATTTCAAGGGAATATCATTATCATTGACGGTGATAGCTACCGTTCTCAGCACCCAAATTACTTAGCTCTGCAAGAA
AAGTATGGTAAGGATAGTGTGGATTATACAAAGGGATTTGCAGGAAAAATGGTAGAGTATCTGGTTGATGAACTCAGTAA
GCAAGGTTATCATTTGTTGATTGAAGGGACTTTGCGAACCACTCAAGTTCCACGGCAGACTGCTCAATTACTACGAAAAA
AAGGCTACCATATTTCTTTGGCTGTGATTGGCACCAAACCAGAACTTTCCTATCTCAGTACCTTGATTCGTTATGAGGAA
CTTTACACAATAAATCCTAATCAGGCCAGAGCAACCCCTAAAGAACATCATGATGGTATTGTAGAGCATTTGGTTGATAA
CCTAAGAGAGTTAGAAAACGATAAGCTCTTTGACCGCATTCAAATTTACCAAAGAGATAGGACTTGTATTTACGATTCTG
AAACGGATGAGATTTCCGCAGCAACAGTTCTTCAAGGATGCCTCTTCGGTAAATGGAGTAAGGTGGAGGAAGAGATGATG
AAGGCGGGAACAGGAACGGTTGAGAGATTTGTGTTGGAAGAACGGTAG
Antitoxin
Download Length: 97 a.a. Molecular weight: 10420.07 Da Isoelectric Point: 7.2040
>AT222722 WP_011260746.1 NZ_CP086200:c2668464-2668174 [Xanthomonas oryzae pv. oryzae]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA
Download Length: 291 bp
>AT222722 NZ_CP118054:c1367023-1366547 [Streptococcus anginosus]
ATGATTGGAGATAATATTAAGTCCTTACGAAAAACTCATGATTTAACCCAGCCAGAATTCGCAAAAATTGTTGGGATTTC
ACGCAATAGCCTAAGTCGATATGAAAATGGAACTAGTTCTGTTTCAACAGAACTCATCGACCGAATTTGTCAGAAATTTA
ATGTTTCATACGTTGATATTGTAGGGGAGGACAAAATGCTAACACCCCTTGAAGATTATCAATTGACCTTAAAAGTAGAA
GTGATAAAAGAACGTGGAGCGGCCATTTTATCCCAACTCTATCGCTACCAAGATAGTCAAGATATTGCTTTTGATGACGA
AACCAATCCTTGGATTTTGATGAGTGATGATTTGGCTGAATTGATCCATACAAAGATTTACCTTGTTGATACTTTCGATG
AAATAGAGCGTTATAATGGCTATTTAGACGGTATAGAGCGGATGTTAGACACGGTGTATCATCGGGTGGTGGCTTGA
ATGATTGGAGATAATATTAAGTCCTTACGAAAAACTCATGATTTAACCCAGCCAGAATTCGCAAAAATTGTTGGGATTTC
ACGCAATAGCCTAAGTCGATATGAAAATGGAACTAGTTCTGTTTCAACAGAACTCATCGACCGAATTTGTCAGAAATTTA
ATGTTTCATACGTTGATATTGTAGGGGAGGACAAAATGCTAACACCCCTTGAAGATTATCAATTGACCTTAAAAGTAGAA
GTGATAAAAGAACGTGGAGCGGCCATTTTATCCCAACTCTATCGCTACCAAGATAGTCAAGATATTGCTTTTGATGACGA
AACCAATCCTTGGATTTTGATGAGTGATGATTTGGCTGAATTGATCCATACAAAGATTTACCTTGTTGATACTTTCGATG
AAATAGAGCGTTATAATGGCTATTTAGACGGTATAGAGCGGATGTTAGACACGGTGTATCATCGGGTGGTGGCTTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|