Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4521767..4522356 Replicon chromosome
Accession NZ_CP086197
Organism Xanthomonas oryzae strain JS97-2

Toxin (Protein)


Gene name graT Uniprot ID A0A8E2YMU3
Locus tag LL929_RS21180 Protein ID WP_011260747.1
Coordinates 4521767..4522048 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LL929_RS21185 Protein ID WP_011260746.1
Coordinates 4522066..4522356 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL929_RS21175 (LL929_21145) 4519420..4521672 + 2253 WP_011409750.1 exodeoxyribonuclease V subunit alpha -
LL929_RS21180 (LL929_21150) 4521767..4522048 + 282 WP_011260747.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LL929_RS21185 (LL929_21155) 4522066..4522356 + 291 WP_011260746.1 HigA family addiction module antitoxin Antitoxin
LL929_RS21190 (LL929_21160) 4523294..4524688 + 1395 WP_027703652.1 type III secretion system effector XopQ -
LL929_RS21195 (LL929_21165) 4524791..4524978 - 188 Protein_4048 hypothetical protein -
LL929_RS21200 (LL929_21170) 4525138..4525470 - 333 WP_011260743.1 hypothetical protein -
LL929_RS21205 (LL929_21175) 4525725..4526051 + 327 WP_228329596.1 hypothetical protein -
LL929_RS21210 (LL929_21180) 4526179..4526601 + 423 WP_042465811.1 PAAR domain-containing protein -
LL929_RS21215 (LL929_21185) 4526604..4527212 + 609 WP_011409746.1 DUF4123 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11070.83 Da        Isoelectric Point: 10.2139

>T222715 WP_011260747.1 NZ_CP086197:4521767-4522048 [Xanthomonas oryzae]
MIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQQRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Download         Length: 282 bp

>T222715 NZ_CP118048:457691-457807 [Enterococcus faecalis]
ATGTTTTTGTCCGTTGAAGCAGCGCTAGGACTGATGATTGGTTTTGCAACGCTTGTTGTGACCATTATCTTCGGTATCTT
AGCGCTTGTCTTAGACAACAAAAATAACCGTTCATAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10420.07 Da        Isoelectric Point: 7.2040

>AT222715 WP_011260746.1 NZ_CP086197:4522066-4522356 [Xanthomonas oryzae]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp

>AT222715 NZ_CP118048:c457923-457718 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAATAGCCACTACCAGTTATAAGAACTGGTGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGCGTTGCAAAACCAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References