Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 2570284..2570873 Replicon chromosome
Accession NZ_CP086196
Organism Xanthomonas oryzae strain KS6-6

Toxin (Protein)


Gene name graT Uniprot ID A0A8E2YMU3
Locus tag LL923_RS11985 Protein ID WP_011260747.1
Coordinates 2570592..2570873 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LL923_RS11980 Protein ID WP_011260746.1
Coordinates 2570284..2570574 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL923_RS11950 (LL923_11940) 2565428..2566036 - 609 WP_011409746.1 DUF4123 domain-containing protein -
LL923_RS11955 (LL923_11945) 2566039..2566461 - 423 WP_042465811.1 PAAR domain-containing protein -
LL923_RS11960 (LL923_11950) 2566589..2566915 - 327 WP_228329596.1 hypothetical protein -
LL923_RS11965 (LL923_11955) 2567170..2567502 + 333 WP_011260743.1 hypothetical protein -
LL923_RS11970 (LL923_11960) 2567662..2567849 + 188 Protein_2286 hypothetical protein -
LL923_RS11975 (LL923_11965) 2567952..2569346 - 1395 WP_027703652.1 type III secretion system effector XopQ -
LL923_RS11980 (LL923_11970) 2570284..2570574 - 291 WP_011260746.1 HigA family addiction module antitoxin Antitoxin
LL923_RS11985 (LL923_11975) 2570592..2570873 - 282 WP_011260747.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LL923_RS11990 (LL923_11980) 2570968..2573220 - 2253 WP_011409750.1 exodeoxyribonuclease V subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11070.83 Da        Isoelectric Point: 10.2139

>T222708 WP_011260747.1 NZ_CP086196:c2570873-2570592 [Xanthomonas oryzae]
MIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQQRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Download         Length: 282 bp

>T222708 NZ_CP118044:c2022378-2022016 [Staphylococcus aureus]
ATGATTAGACGAGGAGATGTTTATTTAGCAGATTTATCACCAGTACAGGGATCTGAACAAGGGGGAGTCAGACCTGTAGT
CATAATTCAAAATGATACTGGTAATAAATATAGTCCTACAGTTATTGTTGCGGCAATAACTGGTAGGATTAATAAAGCGA
AAATACCGACACATGTAGAGATTGAAAAGAAAAAGTATAAATTGGATAAAGACTCAGTTATATTATTAGAACAAATTCGT
ACACTTGATAAAAAACGATTGAAAGAAAAACTGACGTACTTATCCGATGATAAAATGAAAGAAGTAGATAATGCACTAAT
GATTAGTTTAGGGCTGAATGCAGTAGCTCACCAGAAAAATTAG

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10420.07 Da        Isoelectric Point: 7.2040

>AT222708 WP_011260746.1 NZ_CP086196:c2570574-2570284 [Xanthomonas oryzae]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp

>AT222708 NZ_CP118044:c2022545-2022375 [Staphylococcus aureus]
ATGTTATCTTTTAGTCAAAATAGAAGTCATAGCTTAGAACAATCTTTAAAAGAAGGATATTCACAAATGGCTGATTTAAA
TCTCTCCCTAGCGAACGAAGCTTTTCCGATAGAGTGTGAAGCATGCGATTGCAACGAAACATATTTATCTTCTAATTCAA
CGAATGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References