Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4807240..4807829 Replicon chromosome
Accession NZ_CP086195
Organism Xanthomonas oryzae strain JS158-2

Toxin (Protein)


Gene name graT Uniprot ID A0A8E2YMU3
Locus tag LL925_RS22610 Protein ID WP_011260747.1
Coordinates 4807548..4807829 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LL925_RS22605 Protein ID WP_011260746.1
Coordinates 4807240..4807530 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL925_RS22575 (LL925_22550) 4802384..4802992 - 609 WP_011409746.1 DUF4123 domain-containing protein -
LL925_RS22580 (LL925_22555) 4802995..4803417 - 423 WP_042465811.1 PAAR domain-containing protein -
LL925_RS22585 (LL925_22560) 4803545..4803871 - 327 WP_228329596.1 hypothetical protein -
LL925_RS22590 (LL925_22565) 4804126..4804458 + 333 WP_011260743.1 hypothetical protein -
LL925_RS22595 (LL925_22570) 4804618..4804805 + 188 Protein_4314 hypothetical protein -
LL925_RS22600 (LL925_22575) 4804908..4806302 - 1395 WP_027703652.1 type III secretion system effector XopQ -
LL925_RS22605 (LL925_22580) 4807240..4807530 - 291 WP_011260746.1 HigA family addiction module antitoxin Antitoxin
LL925_RS22610 (LL925_22585) 4807548..4807829 - 282 WP_011260747.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LL925_RS22615 (LL925_22590) 4807924..4810176 - 2253 WP_011409750.1 exodeoxyribonuclease V subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11070.83 Da        Isoelectric Point: 10.2139

>T222705 WP_011260747.1 NZ_CP086195:c4807829-4807548 [Xanthomonas oryzae]
MIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQQRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Download         Length: 282 bp

>T222705 NZ_CP118043:c1914900-1914646 [Streptococcus agalactiae]
ATGTTTAATTTTACTGAAGAAGCATGGAAAGATTATGTTTCTTGGCAACAGGAAGATAAAAAAATCTTGAAACGAATTAA
TCGTTTGATAGAAGATATTAAAAGAGACCCATTTGAAGGCATTGGAAAACCAGAACCTTTAAAATACCATTATTCAGGGG
CTTGGTCTCGAAGAATTACAGAAGAACATAGGTTGATTTATATGATAGAAGATGGAGAAATCTATTTTTTATCTTTTAGA
GATCATTATAAGTAG

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10420.07 Da        Isoelectric Point: 7.2040

>AT222705 WP_011260746.1 NZ_CP086195:c4807530-4807240 [Xanthomonas oryzae]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp

>AT222705 NZ_CP118043:c1915159-1914893 [Streptococcus agalactiae]
ATGGAGGCTATTGTTTATTCACATTTTAGAAATAATTTAAAAGATTATATGAAGAAGGTCAATGATGAATTTGAGCCTTT
GATTGTAGTTAATAAAAATCCTGATGAAAATATAGTGGTTTTATCTCAAGATAGCTGGGAAAGTTTACAAGAAACGATTC
GTTTGATGGAAAATGATTATCTATCACATAAGGTTATTAATGGTATATCACAAGTTAAAGAGAAGCAAGTCACTAAACAT
GGTTTAATTGAGGTAGAAGATGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References