Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 309066..309655 Replicon chromosome
Accession NZ_CP086194
Organism Xanthomonas oryzae strain Z173

Toxin (Protein)


Gene name graT Uniprot ID A0A8E2YMU3
Locus tag LL926_RS01420 Protein ID WP_011260747.1
Coordinates 309066..309347 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LL926_RS01425 Protein ID WP_011260746.1
Coordinates 309365..309655 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL926_RS01415 (LL926_01415) 306719..308971 + 2253 WP_011409750.1 exodeoxyribonuclease V subunit alpha -
LL926_RS01420 (LL926_01420) 309066..309347 + 282 WP_011260747.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LL926_RS01425 (LL926_01425) 309365..309655 + 291 WP_011260746.1 HigA family addiction module antitoxin Antitoxin
LL926_RS01430 (LL926_01430) 310593..311987 + 1395 WP_027703652.1 type III secretion system effector XopQ -
LL926_RS01435 (LL926_01435) 312090..312277 - 188 Protein_280 hypothetical protein -
LL926_RS01440 (LL926_01440) 312437..312769 - 333 WP_011260743.1 hypothetical protein -
LL926_RS01445 (LL926_01445) 313024..313350 + 327 WP_228329596.1 hypothetical protein -
LL926_RS01450 (LL926_01450) 313478..313900 + 423 WP_042465811.1 PAAR domain-containing protein -
LL926_RS01455 (LL926_01455) 313903..314511 + 609 WP_011409746.1 DUF4123 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11070.83 Da        Isoelectric Point: 10.2139

>T222696 WP_011260747.1 NZ_CP086194:309066-309347 [Xanthomonas oryzae]
MIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQQRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Download         Length: 282 bp

>T222696 NZ_CP118032:1065663-1065968 [Lactobacillus gasseri]
ATGGCTCAAATTAACTACACTCCTCAATTTAAGCGAGATTATAAGAAGCTTAAAAGAAAACATTATGATTTGAATAAATT
AAAAAATGTCATTCAATTACTTATTGACGAAAAATTTAAAATTCTTGTTGATAAATATGATGACCATCAACTAAAAGGTT
CTTTAAGGTCACTACGTGCATTACATGTTGAGCATAATAAAGCTGGTAATTGGATTTTAGTTTATAAAATTCATAGCGGC
AATTTAGAACTGTTAACCATCGACTTGGTTTCTACTGGTTCCCACGATCATACTTATAGAACATAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10420.07 Da        Isoelectric Point: 7.2040

>AT222696 WP_011260746.1 NZ_CP086194:309365-309655 [Xanthomonas oryzae]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp

>AT222696 NZ_CP118032:1065388-1065663 [Lactobacillus gasseri]
ATGACAACTACCGTAAGTTTAAGATTACCAGAAGATTTAAAGAAACAAGCAACAGATGTATTCAACGAATACGGTCTCGA
TTGGTCATCTGCAATGCGAATGATCTTAACTCAAGTCGTAAGTGAAAATGCAATTCCTGTTAATTTACATAGATATTCTG
AAATTTCTCCTTCGATGAAATCAAATATTGATAGGTCACTTCAAGAATACAAAGCAGGAAATTATAAAACCACAAACTCA
GTAAAAGAGCTATTTGAGGAGTTAGATAAAGACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References