Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4792393..4792982 Replicon chromosome
Accession NZ_CP086184
Organism Xanthomonas oryzae strain PXO280

Toxin (Protein)


Gene name graT Uniprot ID A0A8E2YMU3
Locus tag LL919_RS22410 Protein ID WP_011260747.1
Coordinates 4792393..4792674 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LL919_RS22415 Protein ID WP_011260746.1
Coordinates 4792692..4792982 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL919_RS22405 (LL919_22360) 4790046..4792298 + 2253 WP_044756263.1 exodeoxyribonuclease V subunit alpha -
LL919_RS22410 (LL919_22365) 4792393..4792674 + 282 WP_011260747.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LL919_RS22415 (LL919_22370) 4792692..4792982 + 291 WP_011260746.1 HigA family addiction module antitoxin Antitoxin
LL919_RS22420 (LL919_22375) 4793921..4795315 + 1395 WP_011260745.1 type III secretion system effector XopQ -
LL919_RS22425 (LL919_22380) 4795418..4795605 - 188 Protein_4292 hypothetical protein -
LL919_RS22430 (LL919_22385) 4795765..4796097 - 333 WP_011260743.1 hypothetical protein -
LL919_RS22435 (LL919_22390) 4796352..4796657 + 306 WP_230455549.1 hypothetical protein -
LL919_RS22440 (LL919_22395) 4796807..4797229 + 423 WP_033013301.1 PAAR domain-containing protein -
LL919_RS22445 (LL919_22400) 4797232..4797708 + 477 WP_011260741.1 DUF4123 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11038.77 Da        Isoelectric Point: 10.2139

>T222676 WP_011260747.1 NZ_CP086184:4792393-4792674 [Xanthomonas oryzae]
VIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQQRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Download         Length: 282 bp

>T222676 NZ_CP118014:2512158-2512409 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10420.07 Da        Isoelectric Point: 7.2040

>AT222676 WP_011260746.1 NZ_CP086184:4792692-4792982 [Xanthomonas oryzae]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp

>AT222676 NZ_CP118014:2512406-2512660 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References