Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 5736866..5737434 Replicon chromosome
Accession NZ_CP086106
Organism Skermanella mucosa strain KEMB 2255-438

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag JL100_RS26620 Protein ID WP_202683568.1
Coordinates 5737165..5737434 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag JL100_RS26615 Protein ID WP_202683569.1
Coordinates 5736866..5737168 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JL100_RS26600 (JL100_026665) 5734059..5734391 - 333 WP_202683572.1 sarcosine oxidase subunit delta -
JL100_RS26605 (JL100_026670) 5734413..5735666 - 1254 WP_202683571.1 sarcosine oxidase subunit beta family protein -
JL100_RS26610 (JL100_026675) 5735791..5736699 + 909 WP_202683570.1 EamA family transporter -
JL100_RS26615 (JL100_026680) 5736866..5737168 + 303 WP_202683569.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
JL100_RS26620 (JL100_026685) 5737165..5737434 + 270 WP_202683568.1 Txe/YoeB family addiction module toxin Toxin
JL100_RS26625 (JL100_026690) 5737529..5737906 - 378 WP_202683567.1 hypothetical protein -
JL100_RS26630 (JL100_026695) 5737899..5738189 - 291 WP_202683566.1 DUF6516 family protein -
JL100_RS26635 (JL100_026700) 5738469..5739545 - 1077 WP_202683565.1 GlxA family transcriptional regulator -
JL100_RS26640 (JL100_026705) 5739542..5740537 - 996 WP_228420925.1 GlxA family transcriptional regulator -
JL100_RS26645 (JL100_026710) 5740675..5742390 - 1716 WP_202683563.1 choline dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10722.13 Da        Isoelectric Point: 8.9341

>T222528 WP_202683568.1 NZ_CP086106:5737165-5737434 [Skermanella mucosa]
MTRLAWTDAAWEDYTWWQENDRKTARRINELIKSALRTPFDGVGKPEPLKGDWAGWWSRRITLEHRLVYQISRINGDETL
IIAQCRYHY

Download         Length: 270 bp

>T222528 NZ_CP117959:4355063-4355236 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11193.42 Da        Isoelectric Point: 4.1587

>AT222528 WP_202683569.1 NZ_CP086106:5736866-5737168 [Skermanella mucosa]
MGHVSYTELRQNLARYMDEVCDSNAPLVVTRQNARPVVMISQDEYESMAATLHLIKSPRNALRLIESMEDAEAGRVSERG
LIEVDDEAETDLRTGDGEPD

Download         Length: 303 bp

>AT222528 NZ_CP117959:4354739-4355035 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGATT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAACT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTCAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References