Detailed information of TA system TA222461

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-as-bsrE/-
• Location: 2270845..2271062
• Replicon: chromosome
• Accession: NZ_CP086061
• Organism: Bacillus sp. BC1-43

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: -
• Locus tag: LK685_RS12140
• Protein ID: WP_017696861.1
• Coordinates: 2270845..2271021 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2270962..2271062 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LK685_RS12090 (2266132)	2266132..2266521	-	390	WP_202616987.1	UPF0715 family protein	-
LK685_RS12095 (2266604)	2266604..2266990	-	387	WP_229762359.1	hypothetical protein	-
LK685_RS12100 (2266971)	2266971..2267333	-	363	WP_229762360.1	hypothetical protein	-
LK685_RS12105 (2267371)	2267371..2267730	-	360	WP_213410304.1	hypothetical protein	-
LK685_RS12110 (2267777)	2267777..2268031	-	255	WP_229762361.1	hypothetical protein	-
LK685_RS12115 (2268069)	2268069..2268290	-	222	WP_229762362.1	hypothetical protein	-
LK685_RS12120 (2268287)	2268287..2268739	-	453	WP_229762363.1	hypothetical protein	-
LK685_RS12125 (2269067)	2269067..2270284	-	1218	WP_229762364.1	hypothetical protein	-
LK685_RS12130 (2270372)	2270372..2270530	-	159	WP_069684683.1	hypothetical protein	-
LK685_RS12135 (2270575)	2270575..2270826	-	252	WP_229762365.1	hypothetical protein	-
LK685_RS12140 (2270845)	2270845..2271021	-	177	WP_017696861.1	hypothetical protein	Toxin
- (2270962)	2270962..2271062	+	101	NuclAT_0	-	Antitoxin
- (2270962)	2270962..2271062	+	101	NuclAT_0	-	Antitoxin
- (2270962)	2270962..2271062	+	101	NuclAT_0	-	Antitoxin
- (2270962)	2270962..2271062	+	101	NuclAT_0	-	Antitoxin
LK685_RS12145 (2271896)	2271896..2273470	-	1575	WP_229762366.1	hypothetical protein	-
LK685_RS12150 (2273700)	2273700..2273879	+	180	WP_229762367.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2184888..2341692	156804

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6878.45 Da
• Isoelectric Point: 12.8833

>T222461 WP_017696861.1 NZ_CP086061:c2271021-2270845 [Bacillus sp. BC1-43]
VLEKVGIIVAFLISLTVLTINSLTIVEKIRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Nucleotide

• Length: 177 bp

>T222461 NZ_CP117862:76518-76841 [Komagataeibacter oboediens]
ATGAAGCGAGGCGACTTTGTAACCGTTGCCCTGCAGGACGATCTCGGCAAACCCCAGCCTGCATTGGTGGTGCAGGCTGA
TCGGTTCGACATGACAGCTGTCGTGATCCTCCTGCCTCTCTCCAGCGCCCTTGTGGACGCTCCCCTGCTTCGCCTGACAA
TCCGGCCTGATGAGTACAATGGGCTACGTAAGCCATCACAGGTCATGATCGACAAGCCGACCACCATCAACCGCGAGAAG
GTTGGCCCGGCTTTCGGGATCGCCAGCGATACCCTCATGCTGTCTGTCAGTCGGGCGCTCGCCCTTTTCCTCGGACTGGC
GTAG

Antitoxin

Nucleotide

• Length: 101 bp

>AT222461 NZ_CP086061:2270962-2271062 [Bacillus sp. BC1-43]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTATGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACACAATT

Structures

Antitoxin