Detailed information of TA system TA222452

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2001212..2001458
• Replicon: chromosome
• Accession: NZ_CP086061
• Organism: Bacillus sp. BC1-43

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: LK685_RS10640
• Protein ID: WP_109789044.1
• Coordinates: 2001366..2001458 (-)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2001212..2001385 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LK685_RS10620	1997126..1997683	+	558	WP_004399321.1	SMI1/KNR4 family protein	-
LK685_RS10625	1997785..1999587	+	1803	WP_004399481.1	LXG family T7SS effector ribonuclease toxin YobL	-
LK685_RS10630	1999597..2000055	+	459	WP_003231326.1	type VII secretion system immunity protein YobK	-
LK685_RS10635	2000255..2001097	+	843	WP_003231327.1	hypothetical protein	-
-	2001212..2001385	+	174	-	-	Antitoxin
LK685_RS10640	2001366..2001458	-	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
LK685_RS10645	2001747..2002079	+	333	WP_026009814.1	hypothetical protein	-
LK685_RS10650	2002311..2005916	+	3606	WP_004399367.1	P-loop NTPase fold protein	-
LK685_RS10655	2005963..2006298	-	336	WP_009967409.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1991795..2015472	23677

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T222452 WP_109789044.1 NZ_CP086061:c2001458-2001366 [Bacillus sp. BC1-43]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T222452 NZ_CP117858:c106465-106121 [Komagataeibacter oboediens]
GTGAGCACCAAATCATCGGTCACGTGGATTCCTGACTGCGGCGACATTGTCTGGTTGGAATTTGATCCTCAGGCAGGGCG
GGAGCAGGCTGGACATCGGCCAGCGGTGGTTCTCAGCCCTGCGAGTTATAATGCTAAGGCAGGGATGATGCTTTGCTGCC
CTACGACCACTAAAATCAAAGGCTATCCTTTTGAAGTAGCCGTGGCCGGAAAACCCGCCAGTGTGGTCCTCTCTGATCAG
GTGAGAAGTCTGGACTGGCGGGTGCGGAACGCAAAGCTCAAAGGAAAGATCTCAGCGGAAGAACTCGAAGCAGTTCGTCA
GCGCGCCAGATTACTGGTTGGCTAA

Antitoxin

Nucleotide

• Length: 174 bp

>AT222452 NZ_CP086061:2001212-2001385 [Bacillus sp. BC1-43]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin