Detailed information of TA system TA222108

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 332401..332595
• Replicon: chromosome
• Accession: NZ_CP085841
• Organism: Enterococcus faecalis strain FA2-2

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: LJ570_RS01685
• Protein ID: WP_015543884.1
• Coordinates: 332500..332595 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	332401..332465 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LJ570_RS01670	328019..329761	+	1743	WP_002385355.1	PTS transporter subunit EIIC	-
LJ570_RS01675	329752..331785	+	2034	WP_002361171.1	PRD domain-containing protein	-
LJ570_RS01680	331796..332230	+	435	WP_002358391.1	PTS sugar transporter subunit IIA	-
-	332401..332465	+	65	-	-	Antitoxin
LJ570_RS01685	332500..332595	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
LJ570_RS01690	332841..334613	+	1773	WP_002387897.1	PTS mannitol-specific transporter subunit IIBC	-
LJ570_RS01695	334628..335065	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
LJ570_RS01700	335080..336234	+	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
LJ570_RS01705	336301..337416	-	1116	WP_002380024.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T222108 WP_015543884.1 NZ_CP085841:c332595-332500 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T222108 NZ_CP117693:c3986818-3986531 [Salmonella enterica subsp. enterica serovar London]
ATGCCGATGGAGTTTGAATGGGATGCGAACAAGGCTAAAAGCAACCTGAGGAAGCACGGTGTCCGCTTTGAGGATGCGGT
ACTGGTGTTTGACGATCCCCGACACCTGTCACGTCAGGAGCGTTATGAGAATGGAGAATATCGTTGGCAGACCCTCGGCC
TTGTTCATGGCATTGTGGTCATTCTGGTTGCTCATAGCGTTCGGTTCGAAAGTGGTTTTGAAGTTATCCGTATCATCAGC
GCTCGCAAGGCAGACAGAAAAGAGAGGAATCGTTATGAGCATGGTTAA

Antitoxin

Nucleotide

• Length: 65 bp

>AT222108 NZ_CP085841:332401-332465 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Structures

Antitoxin